Xianghong. Zhu, et.al., A novel in vivo lecithin-cholesterol acyltransferase (LCAT)-deficient mouse expressing predominantly LpX is associated with spontaneous glomerulopathy., The American journal of pathology, 2004, 165

http://rdf.ncbi.nlm.nih.gov/pubmed/15466392

Xianghong. Zhu, et.al., A novel in vivo lecithin-cholesterol acyltransferase (LCAT)-deficient mouse expressing predominantly LpX is associated with spontaneous glomerulopathy., The American journal of pathology, 2004, 165

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• expanded mesangial matrix_Lcat<tm1Hgc>/Lcat<tm1Hgc>
  http://metadb.riken.jp/0011353I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcLcattm1Hgc
• abnormal proximal convoluted tubule morphology_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0004756I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• podocyte foot process effacement_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0008140I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• glomerulosclerosis_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0005264I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• mesangial cell hyperplasia_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0011427I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• albuminuria_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0002871I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• decreased circulating HDL cholesterol level_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0000186I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• mesangial cell hyperplasia_Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0011427I129C57BL6C57BL6JSJLTgSREBP1a7343RehTgSREBP1a7343Reh
• decreased circulating LDL cholesterol level_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0000183I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• mesangial cell hyperplasia_Lcat<tm1Hgc>/Lcat<tm1Hgc>
  http://metadb.riken.jp/0011427I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcLcattm1Hgc
• enlarged liver_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0000599I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• decreased circulating triglyceride level_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0002644I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• expanded mesangial matrix_Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0011353I129C57BL6C57BL6JSJLTgSREBP1a7343RehTgSREBP1a7343Reh
• decreased cholesterol level_Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0003983I129C57BL6C57BL6JSJLTgSREBP1a7343RehTgSREBP1a7343Reh
• increased circulating cholesterol level_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0005178I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• abnormal podocyte morphology_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0005326I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• decreased circulating cholesterol level_Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0005179I129C57BL6C57BL6JSJLTgSREBP1a7343RehTgSREBP1a7343Reh
• abnormal renal glomerulus morphology_Lcat<tm1Hgc>/Lcat<tm1Hgc>
  http://metadb.riken.jp/0005325I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcLcattm1Hgc
• increased circulating VLDL cholesterol level_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0005145I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• decreased circulating HDL cholesterol level_Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0000186I129C57BL6C57BL6JSJLTgSREBP1a7343RehTgSREBP1a7343Reh
• abnormal lipid homeostasis_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0002118I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• abnormal renal glomerulus morphology_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0005325I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• abnormal renal tubule morphology_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0002703I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• increased circulating phospholipid level_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0003980I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• expanded mesangial matrix_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0011353I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc
• enlarged liver_Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0000599I129C57BL6C57BL6JSJLTgSREBP1a7343RehTgSREBP1a7343Reh
• abnormal renal glomerulus morphology_Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0005325I129C57BL6C57BL6JSJLTgSREBP1a7343RehTgSREBP1a7343Reh
• abnormal glomerular capillary morphology_Lcat<tm1Hgc>/Lcat<tm1Hgc>,Tg(SREBP1a)7343Reh/?
  http://metadb.riken.jp/0011320I129C57BL6C57BL6JSJLLcattm1HgcLcattm1HgcTgSREBP1a7343RehTgSREBP1a7343RehLcattm1Hgc