Naoto. Kubota, et.al., Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus., The Journal of clinical investigation, 2004, 114

http://rdf.ncbi.nlm.nih.gov/pubmed/15467830

Naoto. Kubota, et.al., Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus., The Journal of clinical investigation, 2004, 114

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Irs2<tm2Tka>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3497742

class

http://purl.org/net/cito/citesAsAuthority

• Irs2<tm2Tka>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3497742

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased pancreatic beta cell number_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003339I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka
• obese_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001261I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka
• abnormal epididymal fat pad morphology_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0006319I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka
• increased circulating triglyceride level_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001552I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka
• increased circulating leptin level_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005669I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka
• increased body weight_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001260I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka
• impaired glucose tolerance_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka
• increased circulating glucose level_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005559I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka
• increased circulating cholesterol level_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005178I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka
• insulin resistance_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005331I129S4SvJaeC57BL6Irs2tm2TkaIrs2tm2TkaTgIns2cre25Mgn0TgIns2cre25MgnIrs2tm2Tka