Eric E. Zhang, et.al., Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101

http://rdf.ncbi.nlm.nih.gov/pubmed/15520383

Eric E. Zhang, et.al., Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ptpn11<tm1Gsf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522021

class

http://purl.org/net/cito/citesAsAuthority

• Ptpn11<tm1Gsf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522021

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased brown adipose tissue amount_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0000005I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased white adipose tissue amount_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0000008I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• hypoglycemia_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0000189I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• abnormal liver morphology_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0000598I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• enlarged liver_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0000599I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased body length_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0001257I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
他19件を見る
• obese_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0001261I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased circulating triglyceride level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0001552I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• hyperglycemia_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0001559I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• hypersecretion of corticosterone_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0001744I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased circulating corticosterone level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0001745I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• reduced female fertility_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0001923I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• abnormal glucose homeostasis_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0002078I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased circulating insulin level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0002079I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• hepatic steatosis_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0002628I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased circulating thyroid-stimulating hormone level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0005122I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased circulating growth hormone level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0005123I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• abnormal circulating hormone level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0005418I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased susceptibility to weight gain_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0005455I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• decreased circulating thyroxine level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0005478I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• decreased circulating triiodothyronine level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0005479I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• decreased body temperature_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0005534I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased circulating leptin level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0005669I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased liver triglyceride level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0009355I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi
• increased liver glycogen level_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Tg(Camk2a-cre)2Szi/0
  http://metadb.riken.jp/0010400I129S1Sv129X1SvJC57BL6CBAPtpn11tm1GsfPtpn11tm1GsfTgCamk2acre2Szi0Ptpn11tm1GsfTgCamk2acre2Szi