Yonghua. Pan, et.al., gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis., Developmental cell, 2004, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/15525534

Yonghua. Pan, et.al., gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis., Developmental cell, 2004, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Notch2<tm1Rko>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522155

class

http://purl.org/net/cito/citesAsAuthority

• Notch2<tm1Rko>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522155

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent sebaceous gland_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Notch3<Gt(PST033)Byg>/Notch3<Gt(PST033)Byg>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000648I129P2OlaHsd129X1SvJNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoNotch3GtPST033BygNotch3GtPST033BygTgMsx2cre5Rem0TgMsx2cre5RemNotch3GtPST033BygNotch2tm1RkoNotch1tm2Rko
• premature death_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0002083I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• abnormal hair growth_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0002073I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• hair follicle degeneration_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0003413NSNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch2tm1RkoNotch1tm2Rko
• abnormal hair shaft morphology_Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0003809NSNotch1tm2RkoNotch1tm2RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch1tm2Rko
• small sebaceous gland_Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0012725NSNotch1tm2RkoNotch1tm2RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch1tm2Rko
• abnormal hair follicle morphology_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<+>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000377I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2TgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2ShnPsen2
• scaly skin_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Notch3<Gt(PST033)Byg>/Notch3<Gt(PST033)Byg>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001192I129P2OlaHsd129X1SvJNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoNotch3GtPST033BygNotch3GtPST033BygTgMsx2cre5Rem0TgMsx2cre5RemNotch3GtPST033BygNotch2tm1RkoNotch1tm2Rko
• waved hair_Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000410NSNotch1tm2RkoNotch1tm2RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch1tm2Rko
• absent hair follicle inner root sheath_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000388NSNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch2tm1RkoNotch1tm2Rko
• epidermal hyperplasia_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001222I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• thick epidermis_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Notch3<Gt(PST033)Byg>/Notch3<Gt(PST033)Byg>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001219I129P2OlaHsd129X1SvJNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoNotch3GtPST033BygNotch3GtPST033BygTgMsx2cre5Rem0TgMsx2cre5RemNotch3GtPST033BygNotch2tm1RkoNotch1tm2Rko
• absent sebaceous gland_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000648NSNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch2tm1RkoNotch1tm2Rko
• scaly skin_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001192I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• esophagus hyperplasia_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0004546I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• short hair_Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000417NSNotch1tm2RkoNotch1tm2RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch1tm2Rko
• thick epidermis_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001219I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• abnormal hair follicle morphology_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch3<Gt(PST033)Byg>/Notch3<Gt(PST033)Byg>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000377I129P2OlaHsd129X1SvJNotch1tm2RkoNotch1tm2RkoNotch3GtPST033BygNotch3GtPST033BygTgMsx2cre5Rem0Notch1tm2RkoTgMsx2cre5RemNotch3GtPST033Byg
• disorganized inner root sheath cells_Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000387NSNotch1tm2RkoNotch1tm2RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch1tm2Rko
• epidermal cyst_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0003414I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• focal hair loss_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000418I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• premature death_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0002083NSNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch2tm1RkoNotch1tm2Rko
• abnormal hair follicle morphology_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000377I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• decreased body size_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001265I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• hair follicle degeneration_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0003413I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• epidermal hyperplasia_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001222NSNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch2tm1RkoNotch1tm2Rko
• abnormal hair growth_Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0002073NSNotch1tm2RkoNotch1tm2RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch1tm2Rko
• abnormal hair follicle morphology_Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000377NSNotch1tm2RkoNotch1tm2RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch1tm2Rko
• thick skin_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001200I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• no abnormal phenotype detected_Notch2<tm1Rko>/Notch2<tm1Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0002169NSNotch2tm1RkoNotch2tm1RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch2tm1Rko
• scaly skin_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001192NSNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch2tm1RkoNotch1tm2Rko
• short hair_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000417I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• progressive hair loss_Notch1<tm2Rko>/Notch1<tm2Rko>,Notch2<tm1Rko>/Notch2<tm1Rko>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0009004NSNotch1tm2RkoNotch1tm2RkoNotch2tm1RkoNotch2tm1RkoTgMsx2cre5Rem0TgMsx2cre5RemNotch2tm1RkoNotch1tm2Rko
• absent sebocyte_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0013380I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn
• abnormal hair follicle inner root sheath morphology_Psen1<tm2Shn>/Psen1<tm2Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0010685I129S4SvJaePsen1tm2ShnPsen1tm2ShnPsen2tm1HaaPsen2tm1HaaTgMsx2cre5Rem0TgMsx2cre5RemPsen2tm1HaaPsen1tm2Shn