Juan M. Zapata, et.al., TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101

http://rdf.ncbi.nlm.nih.gov/pubmed/15545599

Juan M. Zapata, et.al., TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal spleen marginal zone morphology_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0002362IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• increased marginal zone B cell number_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0008181IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• increased B cell number_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0005014IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• increased small lymphocytic lymphoma incidence_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0009319IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• premature death_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0002083IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• increased B-1a cell number_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0008167IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• decreased B cell apoptosis_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0008783IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• pleural effusion_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0010334IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• enlarged lymph nodes_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0000702IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• increased B-1b cell number_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0008169IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• increased spleen weight_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0004952IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• ascites_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0005324IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• increased chronic lymphocytic leukemia incidence_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0010337IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc
• enlarged spleen_Tg(BCL2/IGH)#Jcre/0,Tg(H2-K/Igh-Traf2*)#Ywc/0
  http://metadb.riken.jp/0000691IBALBcC57BL6CBAJFVBNSJLJSWRJTgBCL2IGHJcre0TgH2KIghTraf2Ywc0TgBCL2IGHJcreTgH2KIghTraf2Ywc