Juhee. Jeong, et.al., Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1., Development (Cambridge, England), 2005, 132

http://rdf.ncbi.nlm.nih.gov/pubmed/15576403

Juhee. Jeong, et.al., Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1., Development (Cambridge, England), 2005, 132

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• incomplete rostral neuropore closure_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0000928I129S1Sv129X1SvJFVBHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Hhiptm1AmcPtch1tm1MpsTgMt1Ptch1MT22Mps
• abnormal neural tube morphology_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<+>
  http://metadb.riken.jp/0002151I129S1Sv129X1SvJHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1Ptch1tm1MpsHhiptm1AmcPtch1
• abnormal neural tube morphology_Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0002151I129S1Sv129X1SvJFVBPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Ptch1tm1MpsTgMt1Ptch1MT22Mps
• abnormal neural tube morphology_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0002151I129S1Sv129X1SvJFVBHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Hhiptm1AmcPtch1tm1MpsTgMt1Ptch1MT22Mps
• exencephaly_Hhip<tm1Amc>/Hhip<+>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0000914I129S1Sv129X1SvJFVBHhiptm1AmcHhipPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0HhipHhiptm1AmcTgMt1Ptch1MT22MpsPtch1tm1Mps
• abnormal pulmonary alveolar duct morphology_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<+>
  http://metadb.riken.jp/0002271I129S1Sv129X1SvJHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1Ptch1tm1MpsHhiptm1AmcPtch1
• spina bifida_Hhip<tm1Amc>/Hhip<+>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0003054I129S1Sv129X1SvJFVBHhiptm1AmcHhipPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0HhipHhiptm1AmcTgMt1Ptch1MT22MpsPtch1tm1Mps
• abnormal diencephalon morphology_Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0000830I129S1Sv129X1SvJFVBPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Ptch1tm1MpsTgMt1Ptch1MT22Mps
• anophthalmia_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0001293I129S1Sv129X1SvJFVBHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Hhiptm1AmcPtch1tm1MpsTgMt1Ptch1MT22Mps
• abnormal neuronal precursor cell number_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0004979I129S1Sv129X1SvJFVBHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Hhiptm1AmcPtch1tm1MpsTgMt1Ptch1MT22Mps
• small first pharyngeal arch_Hhip<tm1Amc>/Hhip<+>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0006341I129S1Sv129X1SvJFVBHhiptm1AmcHhipPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0HhipHhiptm1AmcTgMt1Ptch1MT22MpsPtch1tm1Mps
• enlarged first pharyngeal arch_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0006343I129S1Sv129X1SvJFVBHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Hhiptm1AmcPtch1tm1MpsTgMt1Ptch1MT22Mps
• incomplete rostral neuropore closure_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<+>
  http://metadb.riken.jp/0000928I129S1Sv129X1SvJHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1Ptch1tm1MpsHhiptm1AmcPtch1
• increased embryo size_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<+>
  http://metadb.riken.jp/0001699I129S1Sv129X1SvJHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1Ptch1tm1MpsHhiptm1AmcPtch1
• increased neuronal precursor cell number_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<+>
  http://metadb.riken.jp/0004980I129S1Sv129X1SvJHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1Ptch1tm1MpsHhiptm1AmcPtch1
• enlarged floor plate_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0012675I129S1Sv129X1SvJFVBHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Hhiptm1AmcPtch1tm1MpsTgMt1Ptch1MT22Mps
• abnormal neural tube morphology_Hhip<tm1Amc>/Hhip<+>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0002151I129S1Sv129X1SvJFVBHhiptm1AmcHhipPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0HhipHhiptm1AmcTgMt1Ptch1MT22MpsPtch1tm1Mps
• abnormal neuronal precursor cell number_Hhip<tm1Amc>/Hhip<+>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0004979I129S1Sv129X1SvJFVBHhiptm1AmcHhipPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0HhipHhiptm1AmcTgMt1Ptch1MT22MpsPtch1tm1Mps
• embryonic lethality during organogenesis, incomplete penetrance_Hhip<tm1Amc>/Hhip<tm1Amc>,Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0011108I129S1Sv129X1SvJFVBHhiptm1AmcHhiptm1AmcPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Hhiptm1AmcPtch1tm1MpsTgMt1Ptch1MT22Mps
• abnormal neural tube morphology_Hhip<tm1Amc>/Hhip<tm1Amc>
  http://metadb.riken.jp/0002151I129S1Sv129X1SvJHhiptm1AmcHhiptm1AmcHhiptm1Amc
• abnormal neuronal precursor cell number_Ptch1<tm1Mps>/Ptch1<tm1Mps>,Tg(Mt1-Ptch1)MT22Mps/0
  http://metadb.riken.jp/0004979I129S1Sv129X1SvJFVBPtch1tm1MpsPtch1tm1MpsTgMt1Ptch1MT22Mps0Ptch1tm1MpsTgMt1Ptch1MT22Mps