Joseph H. McCarty, et.al., Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death., Development (Cambridge, England), 2005, 132

http://rdf.ncbi.nlm.nih.gov/pubmed/15576410

Joseph H. McCarty, et.al., Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death., Development (Cambridge, England), 2005, 132

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Itgav<tm2Hyn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759836
• Itgav<tm2.1Hyn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759837

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• demyelination_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000921I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• convulsive seizures_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000947I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• ataxia_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001393I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• impaired coordination_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001405I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• abnormal gait_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001406I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• abnormal posture_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001504I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
他22件を見る
• impaired limb coordination_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001524I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• intracranial hemorrhage_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001915I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• intracranial hemorrhage_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(GFAP-cre)#Gtm/0
  http://metadb.riken.jp/0001915I129P2OlaHsdC57BL6CBAItgavtm2HynItgavtm21HynTgGFAPcreGtm0Itgavtm2HynItgavtm21HynTgGFAPcreGtm
• intracerebral hemorrhage_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001916I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• intracerebral hemorrhage_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(GFAP-cre)#Gtm/0
  http://metadb.riken.jp/0001916I129P2OlaHsdC57BL6CBAItgavtm2HynItgavtm21HynTgGFAPcreGtm0Itgavtm2HynItgavtm21HynTgGFAPcreGtm
• intracerebral hemorrhage_Itgav<tm2.1Hyn>/Itgav<tm2.1Hyn>
  http://metadb.riken.jp/0001916I129P2OlaHsdItgavtm21HynItgavtm21HynItgavtm21Hyn
• seizures_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002064I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• abnormal motor capabilities/coordination/movement_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002066I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• premature death_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002083I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• gliosis_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002183I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• axonal dystrophy_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003225I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• abnormal involuntary movement_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003492I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• abnormal glial cell morphology_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003634I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• muscle hypertonia_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004143I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• abnormal embryonic/fetal subventricular zone morphology_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004274I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• abnormal brain vasculature morphology_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004950I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• axon degeneration_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005405I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• abnormal renal/urinary system physiology_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005502I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• cerebellum hemorrhage_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(GFAP-cre)#Gtm/0
  http://metadb.riken.jp/0006052I129P2OlaHsdC57BL6CBAItgavtm2HynItgavtm21HynTgGFAPcreGtm0Itgavtm2HynItgavtm21HynTgGFAPcreGtm
• spinal hemorrhage_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006054I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• paraparesis_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009434I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn
• increased susceptibility to bacterial infection induced morbidity/mortality_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009788I129P2OlaHsd129S4SvJaeC57BL6FVBSJLItgavtm2HynItgavtm21HynTgNescre1Kln0TgNescre1KlnItgavtm2HynItgavtm21Hyn

class

http://purl.org/net/cito/citesAsAuthority

• Itgav<tm2Hyn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759836
• Itgav<tm2.1Hyn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759837