Despina. Sitara, et.al., Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice., Matrix biology : journal of the International Society for Matrix Biology, 2004, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/15579309

Despina. Sitara, et.al., Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice., Matrix biology : journal of the International Society for Matrix Biology, 2004, 23

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fgf23<tm1Blan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3512143

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• long femur_Fgf23<tm1Blan>/Fgf23<tm1Blan>,Phex<Hyp>/Y
  http://metadb.riken.jp/0004348NSFgf23tm1BlanFgf23tm1BlanPhexHypYPhexHypFgf23tm1Blan
• fragile skeleton_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0000061NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• decreased chondrocyte number_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0000167NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• abnormal femur morphology_Fgf23<tm1Blan>/Fgf23<tm1Blan>,Phex<Hyp>/Y
  http://metadb.riken.jp/0000559NSFgf23tm1BlanFgf23tm1BlanPhexHypYPhexHypFgf23tm1Blan
• abnormal vertebrae morphology_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0000137NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• abnormal bone mineralization_Fgf23<tm1Blan>/Fgf23<tm1Blan>,Phex<Hyp>/Y
  http://metadb.riken.jp/0002896NSFgf23tm1BlanFgf23tm1BlanPhexHypYPhexHypFgf23tm1Blan
• decreased bone mineral density_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0000063NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• abnormal femur morphology_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0000559NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• abnormal bone mineralization_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0002896NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• decreased diameter of femur_Fgf23<tm1Blan>/Fgf23<tm1Blan>,Phex<Hyp>/Y
  http://metadb.riken.jp/0008152NSFgf23tm1BlanFgf23tm1BlanPhexHypYPhexHypFgf23tm1Blan
• decreased long bone epiphyseal plate size_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0006396NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• increased circulating alkaline phosphatase level_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0002968NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• increased diameter of femur_Fgf23<tm1Blan>/Fgf23<+>,Phex<Hyp>/Y
  http://metadb.riken.jp/0008158NSFgf23tm1BlanFgf23PhexHypYFgf23Fgf23tm1BlanPhexHyp
• increased circulating phosphate level_Fgf23<tm1Blan>/Fgf23<tm1Blan>,Phex<Hyp>/Y
  http://metadb.riken.jp/0001566NSFgf23tm1BlanFgf23tm1BlanPhexHypYPhexHypFgf23tm1Blan
• abnormal rib morphology_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0000150NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• thickened long bone epiphysis_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0000132NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• abnormal axial skeleton morphology_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0002114NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• abnormal long bone metaphysis morphology_Fgf23<tm1Blan>/Fgf23<+>,Phex<Hyp>/Y
  http://metadb.riken.jp/0000133NSFgf23tm1BlanFgf23PhexHypYFgf23Fgf23tm1BlanPhexHyp
• abnormal mineral homeostasis_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0005636NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• decreased body weight_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0001262NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• increased bone mineral content_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0010123NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• premature death_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0002083NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• short femur_Fgf23<tm1Blan>/Fgf23<+>,Phex<Hyp>/Y
  http://metadb.riken.jp/0003109NSFgf23tm1BlanFgf23PhexHypYFgf23Fgf23tm1BlanPhexHyp
• increased circulating phosphate level_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0001566NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan
• postnatal growth retardation_Fgf23<tm1Blan>/Fgf23<tm1Blan>
  http://metadb.riken.jp/0001732NSFgf23tm1BlanFgf23tm1BlanFgf23tm1Blan

class

http://purl.org/net/cito/citesAsAuthority

• Fgf23<tm1Blan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3512143