Kurt J. Griffin, et.al., Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors., Cancer research, 2004, 64

http://rdf.ncbi.nlm.nih.gov/pubmed/15604237

Kurt J. Griffin, et.al., Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors., Cancer research, 2004, 64

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Prkar1a*x2as)1Stra
  http://metadb.riken.jp/db/mgi_rdf/MGI:3773697

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Prkar1a*x2as)1Stra
  http://metadb.riken.jp/db/mgi_rdf/MGI:3773697

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• adrenal gland hyperplasia_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0009078IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• pancreas inflammation_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0001869IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• increased lymphoma incidence_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0012431IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• increased liver tumor incidence_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0008019IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• thyroid gland hyperplasia_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0003498IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• abnormal thyroid follicle morphology_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0004696IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• increased spindle cell carcinoma incidence_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0010367IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• abnormal adrenal gland morphology_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0000639IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• increased histiocytic sarcoma incidence_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0009321IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• increased metastatic potential_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0001272IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• increased thyroid adenoma incidence_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0003496IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• abnormal adrenal gland x-zone morphology_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0008296IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• abnormal lymph node morphology_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0002339IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• increased liver adenoma incidence_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0003324IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• increased papilloma incidence_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0002014IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra
• premature death_Tg(CMV-tTA)3Bjd/0,Tg(tetO-Prkar1a*x2as)1Stra/0
  http://metadb.riken.jp/0002083IC57BL6NMRISJLTgCMVtTA3Bjd0TgtetOPrkar1ax2as1Stra0TgCMVtTA3BjdTgtetOPrkar1ax2as1Stra