Xiangdong. Xu, et.al., ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle., Cell, 2005, 120

http://rdf.ncbi.nlm.nih.gov/pubmed/15652482

Xiangdong. Xu, et.al., ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle., Cell, 2005, 120

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Srsf1<tm1Xdfu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530151
• Srsf1<tm1.1Xdfu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530159
• Tg(Myh6-Camk2d)1Xdfu
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530237

class

http://purl.org/net/cito/citesAsAuthority

• Srsf1<tm1Xdfu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530151
• Srsf1<tm1.1Xdfu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530159
• Tg(Myh6-Camk2d)1Xdfu
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530237

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardial fiber morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Srsf1<tm1Xdfu>/Srsf1<tm1Xdfu>
  http://metadb.riken.jp/0000278I129S4SvJaeMyl2tm1creKrcMyl2Srsf1tm1XdfuSrsf1tm1XdfuMyl2Srsf1tm1XdfuMyl2tm1creKrc
• thin ventricular wall_Myl2<tm1(cre)Krc>/Myl2<+>,Srsf1<tm1Xdfu>/Srsf1<tm1Xdfu>
  http://metadb.riken.jp/0000280I129S4SvJaeMyl2tm1creKrcMyl2Srsf1tm1XdfuSrsf1tm1XdfuMyl2Srsf1tm1XdfuMyl2tm1creKrc
• cardiac hypertrophy_Myl2<tm1(cre)Krc>/Myl2<+>,Srsf1<tm1Xdfu>/Srsf1<tm1Xdfu>
  http://metadb.riken.jp/0001625I129S4SvJaeMyl2tm1creKrcMyl2Srsf1tm1XdfuSrsf1tm1XdfuMyl2Srsf1tm1XdfuMyl2tm1creKrc
• premature death_Myl2<tm1(cre)Krc>/Myl2<+>,Srsf1<tm1Xdfu>/Srsf1<tm1Xdfu>
  http://metadb.riken.jp/0002083I129S4SvJaeMyl2tm1creKrcMyl2Srsf1tm1XdfuSrsf1tm1XdfuMyl2Srsf1tm1XdfuMyl2tm1creKrc
• dilated cardiomyopathy_Myl2<tm1(cre)Krc>/Myl2<+>,Srsf1<tm1Xdfu>/Srsf1<tm1Xdfu>
  http://metadb.riken.jp/0002795I129S4SvJaeMyl2tm1creKrcMyl2Srsf1tm1XdfuSrsf1tm1XdfuMyl2Srsf1tm1XdfuMyl2tm1creKrc
• dilated cardiomyopathy_Tg(Myh6-Camk2d)1Xdfu/0
  http://metadb.riken.jp/0002795NSTgMyh6Camk2d1Xdfu0TgMyh6Camk2d1Xdfu
他5件を見る
• abnormal cardiac muscle contractility_Myl2<tm1(cre)Krc>/Myl2<+>,Srsf1<tm1Xdfu>/Srsf1<tm1Xdfu>
  http://metadb.riken.jp/0002972I129S4SvJaeMyl2tm1creKrcMyl2Srsf1tm1XdfuSrsf1tm1XdfuMyl2Srsf1tm1XdfuMyl2tm1creKrc
• abnormal cardiac muscle contractility_Tg(Myh6-Camk2d)1Xdfu/0
  http://metadb.riken.jp/0002972NSTgMyh6Camk2d1Xdfu0TgMyh6Camk2d1Xdfu
• cardiac fibrosis_Myl2<tm1(cre)Krc>/Myl2<+>,Srsf1<tm1Xdfu>/Srsf1<tm1Xdfu>
  http://metadb.riken.jp/0003141I129S4SvJaeMyl2tm1creKrcMyl2Srsf1tm1XdfuSrsf1tm1XdfuMyl2Srsf1tm1XdfuMyl2tm1creKrc
• decreased heart rate_Myl2<tm1(cre)Krc>/Myl2<+>,Srsf1<tm1Xdfu>/Srsf1<tm1Xdfu>
  http://metadb.riken.jp/0005333I129S4SvJaeMyl2tm1creKrcMyl2Srsf1tm1XdfuSrsf1tm1XdfuMyl2Srsf1tm1XdfuMyl2tm1creKrc
• embryonic lethality between implantation and somite formation, complete penetrance_Srsf1<tm1.1Xdfu>/Srsf1<tm1.1Xdfu>
  http://metadb.riken.jp/0011096I129S4SvJaeSrsf1tm11XdfuSrsf1tm11XdfuSrsf1tm11Xdfu