Igor. Kostetskii, et.al., Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure., Circulation research, 2005, 96

http://rdf.ncbi.nlm.nih.gov/pubmed/15662031

Igor. Kostetskii, et.al., Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure., Circulation research, 2005, 96

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdh2<tm1Glr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522469

class

http://purl.org/net/cito/citesAsAuthority

• Cdh2<tm1Glr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522469

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002083I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• abnormal heart shape_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0000277I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• abnormal myocardial fiber morphology_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0000278I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• decreased ventricle muscle contractility_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005598I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• dilated heart left ventricle_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002753I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• abnormal cardiovascular system morphology_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002127I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• decreased cardiac output_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003393I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• abnormal myocardial fiber morphology_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0000278I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• dilated heart right ventricle_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002754I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• dilated heart left ventricle_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002753I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• irregular heartbeat_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0001636I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• abnormal impulse conducting system conduction_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003137I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• increased heart rate_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002626I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• decreased ventricle muscle contractility_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005598I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• abnormal intercalated disc morphology_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0006267I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• abnormal cardiovascular system physiology_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0001544I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• abnormal cardiovascular system physiology_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0001544I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• decreased heart rate_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005333I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• abnormal cardiovascular system morphology_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002127I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• increased heart rate_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002626I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• decreased cardiac output_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003393I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• dilated heart right ventricle_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002754I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• dilated heart atrium_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003140I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• abnormal intercalated disc morphology_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0006267I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• premature death_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002083I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• irregular heartbeat_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0001636I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• abnormal impulse conducting system conduction_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003137I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• abnormal heart shape_Cdh2<tm1Glr>/Cdh2<tm1Hyn>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0000277I129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2tm1HynA1cfTgMyh6creEsr11Jmk0Cdh2tm1HynA1cfTgMyh6creEsr11JmkCdh2tm1Glr
• decreased heart rate_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005333I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk
• dilated heart atrium_Cdh2<tm1Glr>/Cdh2<Gt(OST49160)Lex>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003140I129S5SvEvBrd129S6SvEvTacC57BL6JFVBNCdh2tm1GlrCdh2GtOST49160LexA1cfTgMyh6creEsr11Jmk0Cdh2GtOST49160LexCdh2tm1GlrA1cfTgMyh6creEsr11Jmk