Lutgarde. Serneels, et.al., Differential contribution of the three Aph1 genes to gamma-secretase activity in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102

http://rdf.ncbi.nlm.nih.gov/pubmed/15665098

Lutgarde. Serneels, et.al., Differential contribution of the three Aph1 genes to gamma-secretase activity in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Aph1c<tm1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530441
• Aph1b<tm1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522628
• Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530440
• Aph1c<tm1.1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530442
• Aph1a<tm1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522625

class

http://purl.org/net/cito/citesAsAuthority

• Aph1c<tm1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530441
• Aph1b<tm1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522628
• Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530440
• Aph1c<tm1.1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530442
• Aph1a<tm1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522625

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal somite shape_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0001691I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• kinked neural tube_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0003400I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• embryonic lethality during organogenesis, complete penetrance_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• abnormal vitelline vascular remodeling_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0004076I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• abnormal telencephalon development_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0000934I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• abnormal dermomyotome development_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0004206I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• increased embryonic neuroepithelium apoptosis_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0012701I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• no abnormal phenotype detected_Aph1b<tm1Bdes>/Aph1b<tm1Bdes>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6JAph1btm1BdesAph1btm1BdesAph1btm1Bdes
• abnormal rostral-caudal axis patterning_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0005221I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• abnormal somite development_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0001688I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• distended pericardium_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0000292I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• no abnormal phenotype detected_Aph1b<tm1Bdes>/Aph1b<tm1Bdes>,Aph1c<tm1.1Bdes>/Aph1c<tm1.1Bdes>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6JAph1btm1BdesAph1btm1BdesAph1ctm11BdesAph1ctm11BdesAph1btm1BdesAph1ctm11Bdes
• abnormal embryonic neuroepithelium morphology_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0004261I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• abnormal vascular branching morphogenesis_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0003227I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• no abnormal phenotype detected_Aph1c<tm1Bdes>/Aph1c<tm1Bdes>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6Aph1ctm1BdesAph1ctm1BdesAph1ctm1Bdes
• decreased embryo size_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0001698I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• decreased somite size_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0011732I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• abnormal mesoderm development_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0001680I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• abnormal sclerotome morphology_Aph1a<tm1.1Bdes>/Aph1a<tm1.1Bdes>
  http://metadb.riken.jp/0006029I129P2OlaHsdC57BL6JAph1atm11BdesAph1atm11BdesAph1atm11Bdes
• no abnormal phenotype detected_Aph1a<tm1Bdes>/Aph1a<tm1Bdes>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6Aph1atm1BdesAph1atm1BdesAph1atm1Bdes
• no abnormal phenotype detected_Aph1c<tm1.1Bdes>/Aph1c<tm1.1Bdes>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6JAph1ctm11BdesAph1ctm11BdesAph1ctm11Bdes

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD44760
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD44760
• CD23991
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD23991