Nathalie G. Bérubé, et.al., The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis., The Journal of clinical investigation, 2005, 115

http://rdf.ncbi.nlm.nih.gov/pubmed/15668733

Nathalie G. Bérubé, et.al., The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis., The Journal of clinical investigation, 2005, 115

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Nes-cre)2472Pick
  http://metadb.riken.jp/db/mgi_rdf/MGI:3528493
• Atrx<tm1Rjg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3528480

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Nes-cre)2472Pick
  http://metadb.riken.jp/db/mgi_rdf/MGI:3528493
• Atrx<tm1Rjg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3528480

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal suckling behavior_Atrx<tm1Rjg>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0001436I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAtrxtm1RjgFoxg1
• loss of hippocampal neurons_Atrx<tm1Rjg>/Y,Tg(Nes-cre)2472Pick/0
  http://metadb.riken.jp/0003240I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYTgNescre2472Pick0Atrxtm1RjgTgNescre2472Pick
• postnatal lethality, complete penetrance_Atrx<tm1Rjg>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0011085I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAtrxtm1RjgFoxg1
• loss of cortex neurons_Atrx<tm1Rjg>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0003241I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAtrxtm1RjgFoxg1
• postnatal lethality, incomplete penetrance_Atrx<tm1Rjg>/Y,Tg(Nes-cre)2472Pick/0
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYTgNescre2472Pick0Atrxtm1RjgTgNescre2472Pick
• decreased hippocampus pyramidal cell number_Atrx<tm1Rjg>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0009971I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAtrxtm1RjgFoxg1
• loss of cortex neurons_Atrx<tm1Rjg>/Y,Tg(Nes-cre)2472Pick/0
  http://metadb.riken.jp/0003241I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYTgNescre2472Pick0Atrxtm1RjgTgNescre2472Pick
• loss of hippocampal neurons_Atrx<tm1Rjg>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0003240I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAtrxtm1RjgFoxg1
• absent dentate gyrus_Atrx<tm1Rjg>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0000814I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAtrxtm1RjgFoxg1
• absent gastric milk in neonates_Atrx<tm1Rjg>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0009546I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAtrxtm1RjgFoxg1
• decreased birth body size_Atrx<tm1Rjg>/Y,Tg(Nes-cre)2472Pick/0
  http://metadb.riken.jp/0009703I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYTgNescre2472Pick0Atrxtm1RjgTgNescre2472Pick
• decreased birth body size_Atrx<tm1Rjg>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0009703I129P2OlaHsdC57BL6FVBNAtrxtm1RjgYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAtrxtm1RjgFoxg1