Catherine S. Lee, et.al., Foxa2 is required for the differentiation of pancreatic alpha-cells., Developmental biology, 2005, 278

http://rdf.ncbi.nlm.nih.gov/pubmed/15680365

Catherine S. Lee, et.al., Foxa2 is required for the differentiation of pancreatic alpha-cells., Developmental biology, 2005, 278

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Foxa3-cre)1Khk
  http://metadb.riken.jp/db/mgi_rdf/MGI:2664968

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Foxa3-cre)1Khk
  http://metadb.riken.jp/db/mgi_rdf/MGI:2664968

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• postnatal lethality, complete penetrance_Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Foxa3-cre)1Khk/0
  http://metadb.riken.jp/0011085I129P2OlaHsdC57BL6CD1DBAFoxa2tm1KhkFoxa2tm1KhkTgFoxa3cre1Khk0Foxa2tm1KhkTgFoxa3cre1Khk
• disorganized pancreatic islets_Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Foxa3-cre)1Khk/0
  http://metadb.riken.jp/0009254I129P2OlaHsdC57BL6CD1DBAFoxa2tm1KhkFoxa2tm1KhkTgFoxa3cre1Khk0Foxa2tm1KhkTgFoxa3cre1Khk
• hypoglycemia_Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Foxa3-cre)1Khk/0
  http://metadb.riken.jp/0000189I129P2OlaHsdC57BL6CD1DBAFoxa2tm1KhkFoxa2tm1KhkTgFoxa3cre1Khk0Foxa2tm1KhkTgFoxa3cre1Khk
• decreased pancreatic alpha cell number_Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Foxa3-cre)1Khk/0
  http://metadb.riken.jp/0009177I129P2OlaHsdC57BL6CD1DBAFoxa2tm1KhkFoxa2tm1KhkTgFoxa3cre1Khk0Foxa2tm1KhkTgFoxa3cre1Khk
• decreased circulating glucagon level_Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Foxa3-cre)1Khk/0
  http://metadb.riken.jp/0002696I129P2OlaHsdC57BL6CD1DBAFoxa2tm1KhkFoxa2tm1KhkTgFoxa3cre1Khk0Foxa2tm1KhkTgFoxa3cre1Khk
• decreased body size_Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Foxa3-cre)1Khk/0
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6CD1DBAFoxa2tm1KhkFoxa2tm1KhkTgFoxa3cre1Khk0Foxa2tm1KhkTgFoxa3cre1Khk
• decreased skin turgor_Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Foxa3-cre)1Khk/0
  http://metadb.riken.jp/0003653I129P2OlaHsdC57BL6CD1DBAFoxa2tm1KhkFoxa2tm1KhkTgFoxa3cre1Khk0Foxa2tm1KhkTgFoxa3cre1Khk