Bethany D. Freedman, et.al., A dominant negative peroxisome proliferator-activated receptor-gamma knock-in mouse exhibits features of the metabolic syndrome., The Journal of biological chemistry, 2005, 280

http://rdf.ncbi.nlm.nih.gov/pubmed/15716267

Bethany D. Freedman, et.al., A dominant negative peroxisome proliferator-activated receptor-gamma knock-in mouse exhibits features of the metabolic syndrome., The Journal of biological chemistry, 2005, 280

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pparg<tm1Lja>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3580102

class

http://purl.org/net/cito/citesAsAuthority

• Pparg<tm1Lja>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3580102

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hepatic steatosis_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0002628I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• increased circulating free fatty acid level_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0001554I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• decreased body weight_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• insulin resistance_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0005331I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• increased circulating insulin level_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0002079I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• decreased muscle cell glucose uptake_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0030022I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• decreased total body fat amount_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0010025I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• decreased embryo size_Pparg<tm1Lja>/Pparg<tm1Lja>
  http://metadb.riken.jp/0001698I129S1Sv129X1SvJPpargtm1LjaPpargtm1LjaPpargtm1Lja
• decreased adiponectin level_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0004893I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• increased liver triglyceride level_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0009355I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• abnormal epididymal fat pad morphology_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0006319I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• decreased white fat cell size_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0009133I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• embryonic lethality, complete penetrance_Pparg<tm1Lja>/Pparg<tm1Lja>
  http://metadb.riken.jp/0011092I129S1Sv129X1SvJPpargtm1LjaPpargtm1LjaPpargtm1Lja
• abnormal brown fat cell morphology_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0009116I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• lipodystrophy_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0011174I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja
• hypertension_Pparg<tm1Lja>/Pparg<+>
  http://metadb.riken.jp/0000231I129S1Sv129X1SvJPpargtm1LjaPpargPpargPpargtm1Lja