Tadashi. Okubo, et.al., Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation., Development (Cambridge, England), 2005, 132

http://rdf.ncbi.nlm.nih.gov/pubmed/15716345

Tadashi. Okubo, et.al., Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation., Development (Cambridge, England), 2005, 132

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Sftpc-Nmyc1/EGFP)1Blh
  http://metadb.riken.jp/db/mgi_rdf/MGI:3574950

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Sftpc-Nmyc1/EGFP)1Blh
  http://metadb.riken.jp/db/mgi_rdf/MGI:3574950

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent pulmonary alveoli_Tg(Sftpc-Nmyc1/EGFP)1Blh/0
  http://metadb.riken.jp/0001184IC57BL6DBATgSftpcNmyc1EGFP1Blh0TgSftpcNmyc1EGFP1Blh
• decreased type I pneumocyte number_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0010816I129C57BL6ICRMycntm1PskMycntm1PskTgSftpccre1Blh0Mycntm1PskTgSftpccre1Blh
• abnormal lung morphology_Mycn<tm1Psk>/Mycn<+>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0001175I129C57BL6ICRMycntm1PskMycnTgSftpccre1Blh0TgSftpccre1BlhMycntm1PskMycn
• abnormal branching involved in lung morphogenesis_Mycn<tm1Psk>/Mycn<+>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0011024I129C57BL6ICRMycntm1PskMycnTgSftpccre1Blh0TgSftpccre1BlhMycntm1PskMycn
• abnormal lung epithelium morphology_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0006382I129C57BL6ICRMycntm1PskMycntm1PskTgSftpccre1Blh0Mycntm1PskTgSftpccre1Blh
• neonatal lethality, complete penetrance_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0011087I129C57BL6ICRMycntm1PskMycntm1PskTgSftpccre1Blh0Mycntm1PskTgSftpccre1Blh
• abnormal branching involved in lung morphogenesis_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0011024I129C57BL6ICRMycntm1PskMycntm1PskTgSftpccre1Blh0Mycntm1PskTgSftpccre1Blh
• neonatal lethality, incomplete penetrance_Mycn<tm1Psk>/Mycn<+>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0011088I129C57BL6ICRMycntm1PskMycnTgSftpccre1Blh0TgSftpccre1BlhMycntm1PskMycn
• abnormal lung development_Tg(Sftpc-Nmyc1/EGFP)1Blh/0
  http://metadb.riken.jp/0001176IC57BL6DBATgSftpcNmyc1EGFP1Blh0TgSftpcNmyc1EGFP1Blh
• abnormal lung epithelium morphology_Mycn<tm1Psk>/Mycn<+>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0006382I129C57BL6ICRMycntm1PskMycnTgSftpccre1Blh0TgSftpccre1BlhMycntm1PskMycn
• abnormal lung development_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0001176I129C57BL6ICRMycntm1PskMycntm1PskTgSftpccre1Blh0Mycntm1PskTgSftpccre1Blh
• abnormal lung morphology_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0001175I129C57BL6ICRMycntm1PskMycntm1PskTgSftpccre1Blh0Mycntm1PskTgSftpccre1Blh
• decreased survivor rate_Mycn<tm1Psk>/Mycn<+>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0008770I129C57BL6ICRMycntm1PskMycnTgSftpccre1Blh0TgSftpccre1BlhMycntm1PskMycn
• abnormal pulmonary alveolus epithelial cell morphology_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0002273I129C57BL6ICRMycntm1PskMycntm1PskTgSftpccre1Blh0Mycntm1PskTgSftpccre1Blh
• decreased type II pneumocyte number_Mycn<tm1Psk>/Mycn<+>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0010811I129C57BL6ICRMycntm1PskMycnTgSftpccre1Blh0TgSftpccre1BlhMycntm1PskMycn
• abnormal lung development_Mycn<tm1Psk>/Mycn<+>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0001176I129C57BL6ICRMycntm1PskMycnTgSftpccre1Blh0TgSftpccre1BlhMycntm1PskMycn
• decreased type I pneumocyte number_Mycn<tm1Psk>/Mycn<+>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0010816I129C57BL6ICRMycntm1PskMycnTgSftpccre1Blh0TgSftpccre1BlhMycntm1PskMycn
• decreased type II pneumocyte number_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0010811I129C57BL6ICRMycntm1PskMycntm1PskTgSftpccre1Blh0Mycntm1PskTgSftpccre1Blh

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD02667
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02667
• CD06264
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD06264
• CD38469
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD38469