David R. Powell, et.al., Rapid development of glomerular injury and renal failure in mice lacking p53R2., Pediatric nephrology (Berlin, Germany), 2005, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/15723268

David R. Powell, et.al., Rapid development of glomerular injury and renal failure in mice lacking p53R2., Pediatric nephrology (Berlin, Germany), 2005, 20

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• renal glomerulus fibrosis_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011377I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• decreased circulating alkaline phosphatase level_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0002966I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal compact bone morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0003797I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased blood urea nitrogen level_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0005565I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• thymus atrophy_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0003644I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal glomerular capillary endothelium morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011453I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• enlarged kidney_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0003068I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• hyperlipidemia_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0001548I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal renal glomerulus morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0005325I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased glomerular capsule space_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011501I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal renal tubule morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0002703I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased circulating creatinine level_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0005553I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal urine homeostasis_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0009643I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• kidney failure_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0003606I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased renal glomerulus basement membrane thickness_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011409I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• decreased circulating serum albumin level_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0005419I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased circulating cholesterol level_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0005178I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• podocyte foot process effacement_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0008140I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal glomerular capillary morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011320I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased circulating phosphate level_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0001566I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• renal tubule atrophy_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011346I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal glomerular capsule parietal layer morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011498I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• spleen atrophy_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0003643I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• muscular atrophy_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0002269I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• proximal convoluted tubule brush border loss_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011352I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased renal tubule apoptosis_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0004153I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• podocyte hypertrophy_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011871I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• renal tubular necrosis_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0004154I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal renal tubule epithelium morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0009640I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• decreased circulating glucose level_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0005560I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• decreased total body fat amount_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0010025I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• pale kidney_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0004969I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased urine protein level_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0002962I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal glomerular mesangium morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011339I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• thrombocytosis_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0005505I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• decreased hematocrit_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0000208I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased kidney apoptosis_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011368I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• dilated renal tubules_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0002705I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal glomerular endothelium fenestra morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011454I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• decreased lean body mass_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0003961I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• cortical renal glomerulopathies_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0000523I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• slow postnatal weight gain_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0008489I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased circulating triglyceride level_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0001552I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• premature death_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0002083I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal renal glomerulus basement membrane morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011348I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal renal glomerular capsule morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0002828I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal podocyte morphology_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0005326I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• abnormal blood homeostasis_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0009642I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• increased kidney cell proliferation_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011440I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• decreased glomerular capillary number_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0011359I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex
• decreased hemoglobin content_Rrm2b<Gt(OST85254)Lex>/Rrm2b<Gt(OST85254)Lex>
  http://metadb.riken.jp/0002874I129S5SvEvBrdC57BL6JRrm2bGtOST85254LexRrm2bGtOST85254LexRrm2bGtOST85254Lex