Heiko. Wurdak, et.al., Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome., Genes & development, 2005, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/15741317

Heiko. Wurdak, et.al., Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome., Genes & development, 2005, 19

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal aortic arch and aortic arch branch attachment_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0010464I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• small thymus_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000706I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• abnormal craniofacial bone morphology_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0002116I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• perinatal lethality_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0002081I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• abnormal parathyroid gland morphology_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000678I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• absent parathyroid glands_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000680I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• abnormal hindbrain morphology_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000841I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• abnormal midbrain morphology_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000897I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• abnormal neural crest cell morphology_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0009845I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• abnormal vasodilation_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0001613I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• cleft secondary palate_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0009890I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• parathyroid hypoplasia_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0003494I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• palatal shelves fail to meet at midline_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0009888I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• abnormal blood vessel physiology_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000249I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• ventricular septal defect_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0010402I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• abnormal cartilage morphology_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000163I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• congestive heart failure_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0006138I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• vasculature congestion_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000255I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl
• persistent truncus arteriosis_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0002633I129S1Sv129X1SvJC57BL6CBATgfbr2tm1KarlTgfbr2tm1KarlTgWnt1cre11Rth0TgWnt1cre11RthTgfbr2tm1Karl