W R. MacLellan, et.al., Overlapping roles of pocket proteins in the myocardium are unmasked by germ line deletion of p130 plus heart-specific deletion of Rb., Molecular and cellular biology, 2005, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/15743840

W R. MacLellan, et.al., Overlapping roles of pocket proteins in the myocardium are unmasked by germ line deletion of p130 plus heart-specific deletion of Rb., Molecular and cellular biology, 2005, 25

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased ventricle muscle contractility_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl2<tm1Tyj>/Rbl2<tm1Tyj>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0005598I129129S2SvPasFVBNRb1tm2BrnRb1tm2BrnRbl2tm1TyjRbl2tm1TyjTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182MdsRbl2tm1Tyj
• edema_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl2<tm1Tyj>/Rbl2<tm1Tyj>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0001785I129129S2SvPasFVBNRb1tm2BrnRb1tm2BrnRbl2tm1TyjRbl2tm1TyjTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182MdsRbl2tm1Tyj
• premature death_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl2<tm1Tyj>/Rbl2<tm1Tyj>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0002083I129129S2SvPasFVBNRb1tm2BrnRb1tm2BrnRbl2tm1TyjRbl2tm1TyjTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182MdsRbl2tm1Tyj
• dilated heart left ventricle_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl2<tm1Tyj>/Rbl2<tm1Tyj>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0002753I129129S2SvPasFVBNRb1tm2BrnRb1tm2BrnRbl2tm1TyjRbl2tm1TyjTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182MdsRbl2tm1Tyj
• decreased heart rate_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl2<tm1Tyj>/Rbl2<tm1Tyj>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0005333I129129S2SvPasFVBNRb1tm2BrnRb1tm2BrnRbl2tm1TyjRbl2tm1TyjTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182MdsRbl2tm1Tyj
• no abnormal phenotype detected_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0002169I129FVBRb1tm2BrnRb1tm2BrnTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182Mds
• enlarged myocardial fiber_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl2<tm1Tyj>/Rbl2<tm1Tyj>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0004564I129129S2SvPasFVBNRb1tm2BrnRb1tm2BrnRbl2tm1TyjRbl2tm1TyjTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182MdsRbl2tm1Tyj
• respiratory distress_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl2<tm1Tyj>/Rbl2<tm1Tyj>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0001954I129129S2SvPasFVBNRb1tm2BrnRb1tm2BrnRbl2tm1TyjRbl2tm1TyjTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182MdsRbl2tm1Tyj
• abnormal myocardial fiber physiology_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl2<tm1Tyj>/Rbl2<tm1Tyj>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0004215I129129S2SvPasFVBNRb1tm2BrnRb1tm2BrnRbl2tm1TyjRbl2tm1TyjTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182MdsRbl2tm1Tyj
• enlarged heart_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl2<tm1Tyj>/Rbl2<tm1Tyj>,Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
  http://metadb.riken.jp/0000274I129129S2SvPasFVBNRb1tm2BrnRb1tm2BrnRbl2tm1TyjRbl2tm1TyjTgMyh6cre2182MdsTgMyh6cre2182MdsRb1tm2BrnTgMyh6cre2182MdsRbl2tm1Tyj