Ying-Wei. Lin, et.al., NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia., Blood, 2005, 106

http://rdf.ncbi.nlm.nih.gov/pubmed/15755899

Ying-Wei. Lin, et.al., NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia., Blood, 2005, 106

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Vav1-NUP98/HOXD13)G2Apla
  http://metadb.riken.jp/db/mgi_rdf/MGI:4357686
• Tg(Vav1-NUP98/HOXD13)C1Apla
  http://metadb.riken.jp/db/mgi_rdf/MGI:4357688

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Vav1-NUP98/HOXD13)G2Apla
  http://metadb.riken.jp/db/mgi_rdf/MGI:4357686
• Tg(Vav1-NUP98/HOXD13)C1Apla
  http://metadb.riken.jp/db/mgi_rdf/MGI:4357688

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• giant platelets_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0030025FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• increased nucleated erythrocyte cell number_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0009395FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• decreased neutrophil cell number_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0000222C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• abnormal neutrophil morphology_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0005065C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• polychromatophilia_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0005097FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• increased nucleated erythrocyte cell number_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0009395C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• increased erythroblast number_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0011178FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• premature death_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0002083FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• poikilocytosis_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0002643C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• polychromatophilia_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0005097C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• increased leukemia incidence_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0002026C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• increased mean corpuscular volume_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0002590FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• decreased lymphocyte cell number_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0005016C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• decreased leukocyte cell number_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0000221C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• abnormal definitive hematopoiesis_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0002123FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• abnormal definitive hematopoiesis_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0002123C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• decreased leukocyte cell number_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0000221FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• anemia_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0001577FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• increased leukemia incidence_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0002026FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• poikilocytosis_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0002643FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• premature death_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0002083C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• abnormal megakaryocyte morphology_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0002417FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• increased bone marrow cell number_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0000321FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• abnormal neutrophil morphology_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0005065FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• anisocytosis_Tg(Vav1-NUP98/HOXD13)G2Apla/0
  http://metadb.riken.jp/0002642C57BL6TgVav1NUP98HOXD13G2AplaTgVav1NUP98HOXD13G2Apla0TgVav1NUP98HOXD13G2Apla
• anisocytosis_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0002642FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• abnormal bone marrow cell morphology/development_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0002398FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla
• abnormal erythroid progenitor cell morphology_Tg(Vav1-NUP98/HOXD13)C1Apla/0
  http://metadb.riken.jp/0008801FVBNTgVav1NUP98HOXD13C1AplaTgVav1NUP98HOXD13C1Apla0TgVav1NUP98HOXD13C1Apla