http://rdf.ncbi.nlm.nih.gov/pubmed/15760270

http://rdf.ncbi.nlm.nih.gov/pubmed/15760270

Teresa C. Leone, et.al., PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis., PLoS biology, 2005, 3

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522468

class

http://purl.org/net/cito/citesAsAuthority

• Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3522468

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased thigmotaxis_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0002797I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal body weight_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0001259I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal cerebellum morphology_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0000849I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal basal ganglion morphology_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0006007I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal brainstem morphology_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0005277I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• decreased ventricle muscle contractility_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0005598I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• fatigue_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0002899I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• increased total body fat amount_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0010024I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• hepatic steatosis_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0002628I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• impaired adaptive thermogenesis_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0011049I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• muscle fatigue_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0003646I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal cerebral cortex morphology_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0000788I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal cellular respiration_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0010954I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• decreased cardiac output_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0003393I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• decreased heart rate_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0005333I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal skeletal muscle fiber morphology_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0003084I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• decreased grip strength_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0010053I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• decreased skeletal muscle weight_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0010239I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• increased susceptibility to weight gain_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0005455I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• increased insulin sensitivity_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0002891I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal hippocampus morphology_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0000807I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• increased percent body fat/body weight_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0005458I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal liver physiology_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0000609I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• decreased gastrocnemius weight_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0009422I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• abnormal locomotor behavior_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0001392I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• decreased oxygen consumption_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0005290I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• improved glucose tolerance_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0005292I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• decreased soleus weight_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0009426I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk
• decreased heart weight_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>
  http://metadb.riken.jp/0002834I129X1SvJC57BL6Ppargc1atm1DpkPpargc1atm1DpkPpargc1atm1Dpk