Ikuru. Yazawa, et.al., Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration., Neuron, 2005, 45

http://rdf.ncbi.nlm.nih.gov/pubmed/15797547

Ikuru. Yazawa, et.al., Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration., Neuron, 2005, 45

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• brain atrophy_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0012506IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• abnormal locomotor activation_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0003313IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• demyelination_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0000921IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• alpha-synuclein inclusion body_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0008493IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• decreased oligodendrocyte number_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0009808IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• abnormal spinal cord ventral horn morphology_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0005112IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• neuron degeneration_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0003224IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• axon degeneration_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0005405IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• decreased grip strength_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0010053IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• abnormal myelin sheath morphology_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0003871IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• gliosis_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0002183IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• impaired coordination_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0001405IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• decreased neuron number_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0008948IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• decreased brain weight_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0002175IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle
• abnormal brain white matter morphology_Tg(Cnp-SNCA)M2Vle/Tg(Cnp-SNCA)M2Vle
  http://metadb.riken.jp/0008026IC3HC57BL6TgCnpSNCAM2VleTgCnpSNCAM2VleTgCnpSNCAM2Vle