Katherine. Shim, et.al., Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling., Developmental cell, 2005, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/15809037

Katherine. Shim, et.al., Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling., Developmental cell, 2005, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Spry2<tm1.1Mrt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3578633
• Spry2<tm1Mrt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3578632

class

http://purl.org/net/cito/citesAsAuthority

• Spry2<tm1.1Mrt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3578633
• Spry2<tm1Mrt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3578632

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased cochlear outer hair cell number_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0004401I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• abnormal auditory brainstem response waveform shape_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0011966I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• abnormal Claudius cell morphology_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0004430I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• abnormal digestive system physiology_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0001663I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• abnormal organ of Corti supporting cell morphology_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0004300I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• increased Deiters cell number_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0004840I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• postnatal lethality, incomplete penetrance_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0011086I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• abnormal organ of Corti morphology_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0000042I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• decreased body size_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0001265I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• abnormal pillar cell morphology_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0003825I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt
• increased or absent threshold for auditory brainstem response_Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>
  http://metadb.riken.jp/0011967I129Sv129P2OlaHsdBlackSwissC57BL6FVBNSpry2tm11MrtSpry2tm11MrtSpry2tm11Mrt