Nicoletta. Potenza, et.al., Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice., EMBO reports, 2005, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/15864294

Nicoletta. Potenza, et.al., Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice., EMBO reports, 2005, 6

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3581451
• Kras<tm2(Kras)Rdl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830590

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cardiac fibrosis_Kras<tm1(Hras)Rdl>/Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/0003141EI129S1Sv129X1SvJorI129S1Sv129X1SvJC57BL6Krastm1HrasRdlKrastm1HrasRdlKrastm1HrasRdl
• no abnormal phenotype detected_Kras<tm2(Kras)Rdl>/Kras<tm2(Kras)Rdl>
  http://metadb.riken.jp/0002169E129SvorI129S1Sv129X1SvJC57BL6Krastm2KrasRdlKrastm2KrasRdlKrastm2KrasRdl
• abnormal systemic arterial blood pressure_Kras<tm1(Hras)Rdl>/Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/0000230EI129S1Sv129X1SvJorI129S1Sv129X1SvJC57BL6Krastm1HrasRdlKrastm1HrasRdlKrastm1HrasRdl
• hypertension_Kras<tm1(Hras)Rdl>/Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/0000231EI129S1Sv129X1SvJorI129S1Sv129X1SvJC57BL6Krastm1HrasRdlKrastm1HrasRdlKrastm1HrasRdl
• increased systemic arterial diastolic blood pressure_Kras<tm1(Hras)Rdl>/Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/0006143EI129S1Sv129X1SvJorI129S1Sv129X1SvJC57BL6Krastm1HrasRdlKrastm1HrasRdlKrastm1HrasRdl
• enlarged myocardial fiber_Kras<tm1(Hras)Rdl>/Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/0004564EI129S1Sv129X1SvJorI129S1Sv129X1SvJC57BL6Krastm1HrasRdlKrastm1HrasRdlKrastm1HrasRdl
• dilated cardiomyopathy_Kras<tm1(Hras)Rdl>/Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/0002795EI129S1Sv129X1SvJorI129S1Sv129X1SvJC57BL6Krastm1HrasRdlKrastm1HrasRdlKrastm1HrasRdl
• decreased cardiac muscle contractility_Kras<tm1(Hras)Rdl>/Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/0005140EI129S1Sv129X1SvJorI129S1Sv129X1SvJC57BL6Krastm1HrasRdlKrastm1HrasRdlKrastm1HrasRdl
• increased systemic arterial systolic blood pressure_Kras<tm1(Hras)Rdl>/Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/0006144EI129S1Sv129X1SvJorI129S1Sv129X1SvJC57BL6Krastm1HrasRdlKrastm1HrasRdlKrastm1HrasRdl

class

http://purl.org/net/cito/citesAsAuthority

• Kras<tm1(Hras)Rdl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3581451
• Kras<tm2(Kras)Rdl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830590