Leonard D. Shultz, et.al., Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells., Journal of immunology (Baltimore, Md. : 1950), 2005, 174

http://rdf.ncbi.nlm.nih.gov/pubmed/15879151

Leonard D. Shultz, et.al., Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells., Journal of immunology (Baltimore, Md. : 1950), 2005, 174

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased cellular sensitivity to X-ray irradiation_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002879NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• abnormal response to transplant_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0005671NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• abnormal response to transplant_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0005671NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• spleen hypoplasia_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0000694NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• abnormal lymph node morphology_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002339NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• abnormal thymus morphology_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0000703NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased incidence of tumors by ionizing radiation induction_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0004503NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased CD4-positive, alpha beta T cell number_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008075NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• abnormal response to transplant_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0005671NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• premature death_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002083NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• increased cellular sensitivity to X-ray irradiation_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002879NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased mature B cell number_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008211NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• abnormal spleen B cell follicle morphology_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008470NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased leukocyte cell number_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0000221NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased leukocyte cell number_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0000221NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• abnormal immune system organ morphology_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002722NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• small lymph nodes_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002217NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased incidence of tumors by ionizing radiation induction_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0004503NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• abnormal spleen white pulp morphology_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002357NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• abnormal thymus morphology_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0000703NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• abnormal splenic cell ratio_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008826NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• premature death_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002083NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• increased cellular sensitivity to X-ray irradiation_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002879NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• abnormal splenic cell ratio_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008826NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased CD8-positive, alpha-beta T cell number_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008079NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased mean corpuscular volume_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002591NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased NK cell number_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008045NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• lymph node hypoplasia_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008101NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased CD4-positive, alpha beta T cell number_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008075NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• decreased mean corpuscular volume_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002591NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• premature death_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002083NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased CD4-positive, alpha beta T cell number_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008075NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• lymph node hypoplasia_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008101NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• abnormal spleen B cell follicle morphology_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008470NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased immature B cell number_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008215NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased immunoglobulin level_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002460NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased immunoglobulin level_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002460NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased immature B cell number_Il2rg<tm1Wjl>/Y,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008215NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlYPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• abnormal immune system organ morphology_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002722NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased CD8-positive, alpha-beta T cell number_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008079NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• small lymph nodes_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002217NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• thymus cysts_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0014130NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased mature B cell number_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008211NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• decreased NK cell number_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008045NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• increased T cell derived lymphoma incidence_Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002024NODCB17PrkdcscidPrkdcscidPrkdcscidPrkdcscid
• decreased CD8-positive, alpha-beta T cell number_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008079NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl
• decreased mature B cell number_Il2rg<tm1Wjl>/Il2rg<tm1Wjl>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008211NODCgPrkdcscidIl2rgtm1WjlSzIl2rgtm1WjlIl2rgtm1WjlPrkdcscidPrkdcscidPrkdcscidIl2rgtm1Wjl

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased cellular sensitivity to X-ray irradiation in RBRC01300
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002453
• decreased mature B cell number in RBRC02775
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005089
• increased cellular sensitivity to X-ray irradiation in RBRC06336
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1017467
• decreased mature B cell number in RBRC06336
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1017504
• decreased mature B cell number in RBRC01346
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002559
• abnormal lymph node morphology in RBRC01300
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002443
• decreased mature B cell number in RBRC02771
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005008
• abnormal lymph node morphology in RBRC02775
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005065
• increased cellular sensitivity to X-ray irradiation in RBRC01346
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002545
• premature death in RBRC01346
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010473
• abnormal lymph node morphology in RBRC02771
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004984
• increased cellular sensitivity to X-ray irradiation in RBRC02771
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004994
• abnormal lymph node morphology in RBRC01346
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002535
• increased T cell derived lymphoma incidence in RBRC02775
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010603
• increased T cell derived lymphoma incidence in RBRC01300
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010452
• increased T cell derived lymphoma incidence in RBRC02771
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010586
• abnormal lymph node morphology in RBRC06336
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1017455
• premature death in RBRC02775
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010604
• premature death in RBRC01300
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010453
• premature death in RBRC02771
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010587
• increased T cell derived lymphoma incidence in RBRC01346
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010472
• increased cellular sensitivity to X-ray irradiation in RBRC02775
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005075
• decreased mature B cell number in RBRC01300
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002467