Maki. Nakayama, et.al., Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice., Nature, 2005, 435

http://rdf.ncbi.nlm.nih.gov/pubmed/15889095

Maki. Nakayama, et.al., Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice., Nature, 2005, 435

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• autoimmune response_Ins1<tm1Jja>/Ins1<tm1Jja>,Tg(Ins2*Y16A)3Ell/0
  http://metadb.riken.jp/0001844NODCgIns1tm1JjaTgIns2Y16A3EllIns1tm1JjaIns1tm1JjaTgIns2Y16A3Ell0Ins1tm1JjaTgIns2Y16A3Ell
• decreased anti-insulin autoantibody level_Ins1<tm1Jja>/Ins1<tm1Jja>,Ins2<tm1Jja>/Ins2<tm1Jja>,Tg(Ins2*Y16A)3Ell/0
  http://metadb.riken.jp/0002870NODCgIns1tm1JjaIns2tm1JjaTgIns2Y16A3EllIns1tm1JjaIns1tm1JjaIns2tm1JjaIns2tm1JjaTgIns2Y16A3Ell0TgIns2Y16A3EllIns1tm1JjaIns2tm1Jja
• increased anti-insulin autoantibody level_Ins2<tm1Jja>/Ins2<tm1Jja>,Tg(Ins2*Y16A)3Ell/0
  http://metadb.riken.jp/0002869NODCgIns2tm1JjaTgIns2Y16A3EllIns2tm1JjaIns2tm1JjaTgIns2Y16A3Ell0Ins2tm1JjaTgIns2Y16A3Ell
• increased circulating glucose level_Ins1<tm1Jja>/Ins1<tm1Jja>,Ins2<tm1Jja>/Ins2<tm1Jja>,Tg(Ins2*Y16A)1Ell/0
  http://metadb.riken.jp/0005559NODCgIns1tm1JjaIns2tm1JjaTgIns2Y16A1EllIns1tm1JjaIns1tm1JjaIns2tm1JjaIns2tm1JjaTgIns2Y16A1Ell0Ins2tm1JjaTgIns2Y16A1EllIns1tm1Jja
• increased susceptibility to autoimmune diabetes_Ins1<tm1Jja>/Ins1<tm1Jja>,Tg(Ins2*Y16A)1Ell/0
  http://metadb.riken.jp/0004803NODCgIns1tm1JjaTgIns2Y16A1EllIns1tm1JjaIns1tm1JjaTgIns2Y16A1Ell0Ins1tm1JjaTgIns2Y16A1Ell
• decreased susceptibility to autoimmune diabetes_Ins1<tm1Jja>/Ins1<tm1Jja>,Ins2<tm1Jja>/Ins2<tm1Jja>,Tg(Ins2*Y16A)1Ell/0
  http://metadb.riken.jp/0004804NODCgIns1tm1JjaIns2tm1JjaTgIns2Y16A1EllIns1tm1JjaIns1tm1JjaIns2tm1JjaIns2tm1JjaTgIns2Y16A1Ell0Ins2tm1JjaTgIns2Y16A1EllIns1tm1Jja
• salivary gland inflammation_Ins1<tm1Jja>/Ins1<tm1Jja>,Ins2<tm1Jja>/Ins2<tm1Jja>,Tg(Ins2*Y16A)3Ell/0
  http://metadb.riken.jp/0001870NODCgIns1tm1JjaIns2tm1JjaTgIns2Y16A3EllIns1tm1JjaIns1tm1JjaIns2tm1JjaIns2tm1JjaTgIns2Y16A3Ell0TgIns2Y16A3EllIns1tm1JjaIns2tm1Jja
• increased susceptibility to autoimmune diabetes_Tg(Ins2*Y16A)1Ell/0
  http://metadb.riken.jp/0004803NODTgIns2Y16A1EllTgIns2Y16A1Ell0TgIns2Y16A1Ell
• decreased susceptibility to autoimmune diabetes_Ins1<tm1Jja>/Ins1<tm1Jja>,Ins2<tm1Jja>/Ins2<tm1Jja>,Tg(Ins2*Y16A)3Ell/0
  http://metadb.riken.jp/0004804NODCgIns1tm1JjaIns2tm1JjaTgIns2Y16A3EllIns1tm1JjaIns1tm1JjaIns2tm1JjaIns2tm1JjaTgIns2Y16A3Ell0TgIns2Y16A3EllIns1tm1JjaIns2tm1Jja
• increased susceptibility to autoimmune diabetes_Tg(Ins2*Y16A)3Ell/0
  http://metadb.riken.jp/0004803NODTgIns2Y16A3EllTgIns2Y16A3Ell0TgIns2Y16A3Ell
• salivary gland inflammation_Ins1<tm1Jja>/Ins1<tm1Jja>,Ins2<tm1Jja>/Ins2<tm1Jja>,Tg(Ins2*Y16A)1Ell/0
  http://metadb.riken.jp/0001870NODCgIns1tm1JjaIns2tm1JjaTgIns2Y16A1EllIns1tm1JjaIns1tm1JjaIns2tm1JjaIns2tm1JjaTgIns2Y16A1Ell0Ins2tm1JjaTgIns2Y16A1EllIns1tm1Jja
• autoimmune response_Ins2<tm1Jja>/Ins2<tm1Jja>,Tg(Ins2*Y16A)3Ell/0
  http://metadb.riken.jp/0001844NODCgIns2tm1JjaTgIns2Y16A3EllIns2tm1JjaIns2tm1JjaTgIns2Y16A3Ell0Ins2tm1JjaTgIns2Y16A3Ell
• increased circulating glucose level_Ins1<tm1Jja>/Ins1<tm1Jja>,Tg(Ins2*Y16A)1Ell/0
  http://metadb.riken.jp/0005559NODCgIns1tm1JjaTgIns2Y16A1EllIns1tm1JjaIns1tm1JjaTgIns2Y16A1Ell0Ins1tm1JjaTgIns2Y16A1Ell