Sunil R. Hingorani, et.al., Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice., Cancer cell, 2005, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/15894267

Sunil R. Hingorani, et.al., Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice., Cancer cell, 2005, 7

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cachexia_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0005150I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009152I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• increased pancreatic ductal adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009151I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• hemorrhagic ascites_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0013184I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• increased papilloma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0002014I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009152I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKras
• chromosomal instability_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0008866I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• distended abdomen_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0001270I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• cholestasis_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0000610I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• increased T cell derived lymphoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0002024I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• premature death_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• increased teratocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0010349I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• increased esophageal papilloma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0003277I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53
• intestinal obstruction_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0003270I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm2TyjTrp53TgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvTrp53tm2TyjTrp53