Tang-Long. Shen, et.al., Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis., The Journal of cell biology, 2005, 169

http://rdf.ncbi.nlm.nih.gov/pubmed/15967814

Tang-Long. Shen, et.al., Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis., The Journal of cell biology, 2005, 169

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ptk2<tm1.2Guan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3583807
• Ptk2<tm1.1Guan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3583806

class

http://purl.org/net/cito/citesAsAuthority

• Ptk2<tm1.2Guan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3583807
• Ptk2<tm1.1Guan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3583806

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal placenta vasculature_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0003231I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• thick dermal layer_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001245I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• hemorrhage_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001914I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• thin placenta labyrinth_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0011523I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• edema_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001785I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• abnormal amnion morphology_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0005029I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• lethality throughout fetal growth and development, incomplete penetrance_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0011109I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• abnormal capillary morphology_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0003658I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• abnormal vascular endothelial cell morphology_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0006055I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• decreased embryo size_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001698I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• abnormal vitelline vasculature morphology_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0003229I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• embryonic lethality during organogenesis, complete penetrance_Ptk2<tm1.2Guan>/Ptk2<tm1.2Guan>
  http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6JPtk2tm12GuanPtk2tm12GuanPtk2tm12Guan
• abnormal vascular branching morphogenesis_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0003227I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• embryonic growth retardation_Ptk2<tm1.1Guan>/Ptk2<tm1.2Guan>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0003984I129P2OlaHsdC3HC57BL6C57BL6JPtk2tm11GuanPtk2tm12GuanTgTekcre12Flv0TgTekcre12FlvPtk2tm11GuanPtk2tm12Guan
• embryonic growth retardation_Ptk2<tm1.2Guan>/Ptk2<tm1.2Guan>
  http://metadb.riken.jp/0003984I129P2OlaHsdC57BL6JPtk2tm12GuanPtk2tm12GuanPtk2tm12Guan