Yingli. Wang, et.al., Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse., Development (Cambridge, England), 2005, 132

http://rdf.ncbi.nlm.nih.gov/pubmed/15975938

Yingli. Wang, et.al., Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse., Development (Cambridge, England), 2005, 132

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fgfr2<tm1Ewj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3603464

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal zygomatic arch morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0004469I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal sagittal suture morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0003843I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal parietal bone morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000109I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal maxilla morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000455I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal cranial suture morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0002835I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal nasal bone morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000102I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• hydroencephaly_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0001891I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• aerophagia_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0010994I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal long bone hypertrophic chondrocyte zone_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000165I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal mandible morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000458I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal facial morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0003743I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal interparietal bone morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000077I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal coronal suture morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0003840I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• decreased birth weight_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0009674I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal craniofacial bone morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0002116I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal osteoblast differentiation_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0008395I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal basicranium morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0010029I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• decreased body length_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0001258I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• meteorism_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0009247I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• neonatal lethality, complete penetrance_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal tracheal cartilage morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0003120I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal mandibular angle morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0004596I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal cartilage morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000163I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• small mandible_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0004592I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• decreased osteoclast cell number_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0004985I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal head morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000432I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal palate morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0003755I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• bronchiolectasis_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0011013I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• respiratory failure_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0001953I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal metopic suture morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0003842I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal neurocranium morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000074I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal lambdoidal suture morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0003841I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• small cranium_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0005352I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• premature suture closure_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000081I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• atelectasis_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0001177I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal vasodilation_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0001613I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• short maxilla_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000097I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• decreased body weight_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• dilated heart atrium_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0003140I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal cartilage development_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000164I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• abnormal thymus morphology_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0000703I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2
• pulmonary alveolar proteinosis_Fgfr2<tm1Ewj>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0010998I129S1Sv129X1SvJC57BL6JFVBNFgfr2tm1EwjFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2tm1EwjFgfr2

class

http://purl.org/net/cito/citesAsAuthority

• Fgfr2<tm1Ewj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3603464