Silvia. Grisendi, et.al., Role of nucleophosmin in embryonic development and tumorigenesis., Nature, 2005, 437

http://rdf.ncbi.nlm.nih.gov/pubmed/16007073

Silvia. Grisendi, et.al., Role of nucleophosmin in embryonic development and tumorigenesis., Nature, 2005, 437

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Npm1<tm2Ppp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3604808
• Npm1<tm1Ppp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3604807

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal forebrain development_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0003232I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• anemia_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0001577I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• abnormal visceral yolk sac blood island morphology_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0011204I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• abnormal tumor morphology_Npm1<tm1Ppp>/Npm1<+>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0003448I129S1SvC57BL6SJLNpm1tm1PppNpm1TgIghMyc22Bri0Npm1Npm1tm1PppTgIghMyc22Bri
• absent forebrain_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0012136I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• lethality throughout fetal growth and development, complete penetrance_Npm1<tm1Ppp>/Npm1<tm1Ppp>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0011099I129S1Sv129S7SvEvBrdC57BL6Npm1tm1PppNpm1tm1PppTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdNpm1tm1Ppp
• abnormal embryonic hematopoiesis_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0003396I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• absent liver_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0011877I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• abnormal cell cycle_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0003077I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• abnormal vitelline vasculature morphology_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0003229I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• increased B cell derived lymphoma incidence_Npm1<tm1Ppp>/Npm1<+>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0002023I129S1SvC57BL6SJLNpm1tm1PppNpm1TgIghMyc22Bri0Npm1Npm1tm1PppTgIghMyc22Bri
• pallor_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0003717I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• abnormal embryonic hematopoiesis_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0003396I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• pallor_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0003717I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• chromosome breakage_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0004028I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• decreased fibroblast proliferation_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0011704I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• abnormal brain morphology_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0002152I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• decreased fibroblast proliferation_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0011704I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• decreased embryo size_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0001698I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• small placenta_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0004259I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• abnormal eye development_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0001286I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• increased fibroblast proliferation_Npm1<tm1Ppp>/Npm1<+>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0011703I129S1Sv129S7SvEvBrdC57BL6Npm1tm1PppNpm1Trp53tm1BrdTrp53tm1BrdNpm1tm1PppTrp53tm1BrdNpm1
• lethality throughout fetal growth and development, complete penetrance_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0011099I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• anemia_Npm1<tm2Ppp>/Npm1<tm2Ppp>
  http://metadb.riken.jp/0001577I129S1SvC57BL6Npm1tm2PppNpm1tm2PppNpm1tm2Ppp
• absent vitelline blood vessels_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0001719I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• increased embryonic tissue cell apoptosis_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0013504I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• anophthalmia_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0001293I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• embryonic lethality during organogenesis, complete penetrance_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0011098I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp
• embryonic lethality, complete penetrance_Npm1<tm1Ppp>/Npm1<tm1Ppp>,Trp53<tm1Brd>/Trp53<+>
  http://metadb.riken.jp/0011092I129S1Sv129S7SvEvBrdC57BL6Npm1tm1PppNpm1tm1PppTrp53tm1BrdTrp53Npm1tm1PppTrp53tm1BrdTrp53
• decreased embryo size_Npm1<tm1Ppp>/Npm1<tm1Ppp>
  http://metadb.riken.jp/0001698I129S1SvC57BL6Npm1tm1PppNpm1tm1PppNpm1tm1Ppp

class

http://purl.org/net/cito/citesAsAuthority

• Npm1<tm2Ppp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3604808
• Npm1<tm1Ppp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3604807