K. Santacruz, et.al., Tau suppression in a neurodegenerative mouse model improves memory function., Science (New York, N.Y.), 2005, 309

http://rdf.ncbi.nlm.nih.gov/pubmed/16020737

K. Santacruz, et.al., Tau suppression in a neurodegenerative mouse model improves memory function., Science (New York, N.Y.), 2005, 309

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-MAPT*P301L)#Kha
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819866

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-MAPT*P301L)#Kha
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819866

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron morphology_Tg(Camk2a-tTA)1Mmay/?,Tg(tetO-MAPT*P301L)#Kha/?
  http://metadb.riken.jp/0002882I129S6SvEvTacFVBNTgCamk2atTA1MmayTgtetOMAPTP301LKhaTgCamk2atTA1MmayTgtetOMAPTP301LKha
• forebrain atrophy_Tg(Camk2a-tTA)1Mmay/?,Tg(tetO-MAPT*P301L)#Kha/?
  http://metadb.riken.jp/0012508I129S6SvEvTacFVBNTgCamk2atTA1MmayTgtetOMAPTP301LKhaTgCamk2atTA1MmayTgtetOMAPTP301LKha
• decreased brain weight_Tg(Camk2a-tTA)1Mmay/?,Tg(tetO-MAPT*P301L)#Kha/?
  http://metadb.riken.jp/0002175I129S6SvEvTacFVBNTgCamk2atTA1MmayTgtetOMAPTP301LKhaTgCamk2atTA1MmayTgtetOMAPTP301LKha
• abnormal spatial learning_Tg(Camk2a-tTA)1Mmay/?,Tg(tetO-MAPT*P301L)#Kha/?
  http://metadb.riken.jp/0001463I129S6SvEvTacFVBNTgCamk2atTA1MmayTgtetOMAPTP301LKhaTgCamk2atTA1MmayTgtetOMAPTP301LKha
• abnormal hippocampus CA1 region morphology_Tg(Camk2a-tTA)1Mmay/?,Tg(tetO-MAPT*P301L)#Kha/?
  http://metadb.riken.jp/0008263I129S6SvEvTacFVBNTgCamk2atTA1MmayTgtetOMAPTP301LKhaTgCamk2atTA1MmayTgtetOMAPTP301LKha
• neurofibrillary tangles_Tg(Camk2a-tTA)1Mmay/?,Tg(tetO-MAPT*P301L)#Kha/?
  http://metadb.riken.jp/0003214I129S6SvEvTacFVBNTgCamk2atTA1MmayTgtetOMAPTP301LKhaTgCamk2atTA1MmayTgtetOMAPTP301LKha
• decreased hippocampus pyramidal cell number_Tg(Camk2a-tTA)1Mmay/?,Tg(tetO-MAPT*P301L)#Kha/?
  http://metadb.riken.jp/0009971I129S6SvEvTacFVBNTgCamk2atTA1MmayTgtetOMAPTP301LKhaTgCamk2atTA1MmayTgtetOMAPTP301LKha