Philip. Van Damme, et.al., GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis., Journal of neuropathology and experimental neurology, 2005, 64

http://rdf.ncbi.nlm.nih.gov/pubmed/16042312

Philip. Van Damme, et.al., GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis., Journal of neuropathology and experimental neurology, 2005, 64

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal AMPA-mediated synaptic currents_Gria2<tm1Rod>/Gria2<tm1Rod>
  http://metadb.riken.jp/0002885B6129Gria2tm1RodJGria2tm1RodGria2tm1RodGria2tm1Rod
• abnormal AMPA-mediated synaptic currents_Gria2<tm1Rod>/Gria2<tm1Rod>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0002885B6CgGria2tm1RodTgSOD1G93A1GurGria2tm1RodGria2tm1RodTgSOD1G93A1Gur0Gria2tm1RodTgSOD1G93A1Gur
• premature death_Gria2<tm1Rod>/Gria2<tm1Rod>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0002083B6CgGria2tm1RodTgSOD1G93A1GurGria2tm1RodGria2tm1RodTgSOD1G93A1Gur0Gria2tm1RodTgSOD1G93A1Gur
• increased susceptibility to neuronal excitotoxicity_Gria2<tm1Rod>/Gria2<tm1Rod>
  http://metadb.riken.jp/0008235B6129Gria2tm1RodJGria2tm1RodGria2tm1RodGria2tm1Rod
• decreased grip strength_Gria2<tm1Rod>/Gria2<tm1Rod>
  http://metadb.riken.jp/0010053B6129Gria2tm1RodJGria2tm1RodGria2tm1RodGria2tm1Rod
• hindlimb paralysis_Gria2<tm1Rod>/Gria2<tm1Rod>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0000755B6CgGria2tm1RodTgSOD1G93A1GurGria2tm1RodGria2tm1RodTgSOD1G93A1Gur0Gria2tm1RodTgSOD1G93A1Gur
• abnormal AMPA-mediated synaptic currents_Gria2<tm1Rod>/Gria2<+>
  http://metadb.riken.jp/0002885B6129Gria2tm1RodJGria2tm1RodGria2Gria2Gria2tm1Rod
• increased susceptibility to neuronal excitotoxicity_Gria2<tm1Rod>/Gria2<+>
  http://metadb.riken.jp/0008235B6129Gria2tm1RodJGria2tm1RodGria2Gria2Gria2tm1Rod
• decreased grip strength_Gria2<tm1Rod>/Gria2<tm1Rod>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0010053B6CgGria2tm1RodTgSOD1G93A1GurGria2tm1RodGria2tm1RodTgSOD1G93A1Gur0Gria2tm1RodTgSOD1G93A1Gur
• decreased motor neuron number_Gria2<tm1Rod>/Gria2<tm1Rod>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0000939B6CgGria2tm1RodTgSOD1G93A1GurGria2tm1RodGria2tm1RodTgSOD1G93A1Gur0Gria2tm1RodTgSOD1G93A1Gur
• abnormal response to novel object_Gria2<tm1Rod>/Gria2<tm1Rod>
  http://metadb.riken.jp/0003461B6129Gria2tm1RodJGria2tm1RodGria2tm1RodGria2tm1Rod
• abnormal limb posture_Gria2<tm1Rod>/Gria2<tm1Rod>
  http://metadb.riken.jp/0004263B6129Gria2tm1RodJGria2tm1RodGria2tm1RodGria2tm1Rod
• decreased motor neuron number_Gria2<tm1Rod>/Gria2<+>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0000939B6CgGria2tm1RodTgSOD1G93A1GurGria2tm1RodGria2TgSOD1G93A1Gur0TgSOD1G93A1GurGria2tm1RodGria2
• hypoactivity_Gria2<tm1Rod>/Gria2<tm1Rod>
  http://metadb.riken.jp/0001402B6129Gria2tm1RodJGria2tm1RodGria2tm1RodGria2tm1Rod
• impaired coordination_Gria2<tm1Rod>/Gria2<tm1Rod>
  http://metadb.riken.jp/0001405B6129Gria2tm1RodJGria2tm1RodGria2tm1RodGria2tm1Rod
• impaired coordination_Gria2<tm1Rod>/Gria2<tm1Rod>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0001405B6CgGria2tm1RodTgSOD1G93A1GurGria2tm1RodGria2tm1RodTgSOD1G93A1Gur0Gria2tm1RodTgSOD1G93A1Gur