Adriana. Donovan, et.al., The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis., Cell metabolism, 2005, 1

http://rdf.ncbi.nlm.nih.gov/pubmed/16054062

Adriana. Donovan, et.al., The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis., Cell metabolism, 2005, 1

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Slc40a1<tm2Nca>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771548
• Slc40a1<tm1Nca>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771547

class

http://purl.org/net/cito/citesAsAuthority

• Slc40a1<tm2Nca>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771548
• Slc40a1<tm1Nca>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771547

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality between implantation and somite formation, incomplete penetrance_Slc40a1<tm1Nca>/Slc40a1<tm1Nca>
  http://metadb.riken.jp/0011106I129S4SvJae129S6SvEvTacSlc40a1tm1NcaSlc40a1tm1NcaSlc40a1tm1Nca
• anisocytosis_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0002642I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• decreased embryo size_Slc40a1<tm1Nca>/Slc40a1<tm1Nca>
  http://metadb.riken.jp/0001698I129S4SvJae129S6SvEvTacSlc40a1tm1NcaSlc40a1tm1NcaSlc40a1tm1Nca
• prenatal lethality, complete penetrance_Slc40a1<tm2Nca>/Slc40a1<tm2Nca>,Tg(Vil-cre)20Syr/0
  http://metadb.riken.jp/0011091I129S4SvJae129S6SvEvTacC57BL6DBA2Slc40a1tm2NcaSlc40a1tm2NcaTgVilcre20Syr0Slc40a1tm2NcaTgVilcre20Syr
• decreased spleen iron level_Slc40a1<tm2Nca>/Slc40a1<tm2Nca>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0008808I129S4SvJae129S6SvEvTacC57BL6DBA2Slc40a1tm2NcaSlc40a1tm2NcaTgVilcreERT223Syr0TgVilcreERT223SyrSlc40a1tm2Nca
• increased intestinal iron level_Slc40a1<tm2Nca>/Slc40a1<tm2Nca>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0020369I129S4SvJae129S6SvEvTacC57BL6DBA2Slc40a1tm2NcaSlc40a1tm2NcaTgVilcreERT223Syr0TgVilcreERT223SyrSlc40a1tm2Nca
• anemia_Slc40a1<tm2Nca>/Slc40a1<tm2Nca>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0001577I129S4SvJae129S6SvEvTacC57BL6DBA2Slc40a1tm2NcaSlc40a1tm2NcaTgVilcreERT223Syr0TgVilcreERT223SyrSlc40a1tm2Nca
• decreased body size_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0001265I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• poikilocytosis_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0002643I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• decreased liver iron level_Slc40a1<tm1Nca>/Slc40a1<+>
  http://metadb.riken.jp/0008743I129S4SvJae129S6SvEvTacSlc40a1tm1NcaSlc40a1Slc40a1tm1NcaSlc40a1
• anemia_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0001577I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• pallor_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0003717I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• decreased hemoglobin content_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0002874I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• decreased hematocrit_Slc40a1<tm2Nca>/Slc40a1<tm2Nca>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0000208I129S4SvJae129S6SvEvTacC57BL6DBA2Slc40a1tm2NcaSlc40a1tm2NcaTgVilcreERT223Syr0TgVilcreERT223SyrSlc40a1tm2Nca
• decreased hemoglobin content_Slc40a1<tm2Nca>/Slc40a1<tm2Nca>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0002874I129S4SvJae129S6SvEvTacC57BL6DBA2Slc40a1tm2NcaSlc40a1tm2NcaTgVilcreERT223Syr0TgVilcreERT223SyrSlc40a1tm2Nca
• reticulocytosis_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0002640I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• increased intestinal iron level_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0020369I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• decreased liver iron level_Slc40a1<tm2Nca>/Slc40a1<tm2Nca>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0008743I129S4SvJae129S6SvEvTacC57BL6DBA2Slc40a1tm2NcaSlc40a1tm2NcaTgVilcreERT223Syr0TgVilcreERT223SyrSlc40a1tm2Nca
• abnormal erythrocyte morphology_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0002447I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• increased spleen iron level_Slc40a1<tm1Nca>/Slc40a1<+>
  http://metadb.riken.jp/0008809I129S4SvJae129S6SvEvTacSlc40a1tm1NcaSlc40a1Slc40a1tm1NcaSlc40a1
• increased spleen iron level_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0008809I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• decreased mean corpuscular volume_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0002591I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• decreased mean corpuscular volume_Slc40a1<tm1Nca>/Slc40a1<+>
  http://metadb.riken.jp/0002591I129S4SvJae129S6SvEvTacSlc40a1tm1NcaSlc40a1Slc40a1tm1NcaSlc40a1
• decreased hemoglobin content_Slc40a1<tm1Nca>/Slc40a1<+>
  http://metadb.riken.jp/0002874I129S4SvJae129S6SvEvTacSlc40a1tm1NcaSlc40a1Slc40a1tm1NcaSlc40a1
• abnormal liver iron level_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0008738I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor
• decreased mean corpuscular hemoglobin_Meox2<tm1(cre)Sor>/Meox2<+>,Slc40a1<tm2Nca>/Slc40a1<tm2Nca>
  http://metadb.riken.jp/0005562I129S4SvJae129S6SvEvTacMeox2tm1creSorMeox2Slc40a1tm2NcaSlc40a1tm2NcaMeox2Slc40a1tm2NcaMeox2tm1creSor