G. Malek, et.al., Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102

http://rdf.ncbi.nlm.nih.gov/pubmed/16079201

G. Malek, et.al., Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• retinal degeneration_Apoe<tm1(APOE*2)Mae>/Apoe<tm1(APOE*2)Mae>
  http://metadb.riken.jp/0001326I129P2OlaHsdC57BL6Apoetm1APOE2MaeApoetm1APOE2MaeApoetm1APOE2Mae
• retinal pigment epithelium atrophy_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>
  http://metadb.riken.jp/0005548I129P2OlaHsdC57BL6Apoetm3APOE4MaeApoetm3APOE4MaeApoetm3APOE4Mae
• abnormal Bruch membrane morphology_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>
  http://metadb.riken.jp/0005239I129P2OlaHsdC57BL6Apoetm3APOE4MaeApoetm3APOE4MaeApoetm3APOE4Mae
• abnormal retinal pigment epithelium morphology_Apoe<tm2(APOE*3)Mae>/Apoe<tm2(APOE*3)Mae>
  http://metadb.riken.jp/0005201I129P2OlaHsdC57BL6Apoetm2APOE3MaeApoetm2APOE3MaeApoetm2APOE3Mae
• abnormal retinal pigment epithelium morphology_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>
  http://metadb.riken.jp/0005201I129P2OlaHsdC57BL6Apoetm3APOE4MaeApoetm3APOE4MaeApoetm3APOE4Mae
• thin retinal outer nuclear layer_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>
  http://metadb.riken.jp/0008515I129P2OlaHsdC57BL6Apoetm3APOE4MaeApoetm3APOE4MaeApoetm3APOE4Mae
• abnormal retinal pigment epithelium morphology_Apoe<tm1(APOE*2)Mae>/Apoe<tm1(APOE*2)Mae>
  http://metadb.riken.jp/0005201I129P2OlaHsdC57BL6Apoetm1APOE2MaeApoetm1APOE2MaeApoetm1APOE2Mae
• retinal degeneration_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>
  http://metadb.riken.jp/0001326I129P2OlaHsdC57BL6Apoetm3APOE4MaeApoetm3APOE4MaeApoetm3APOE4Mae
• retinal neovascularization_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>
  http://metadb.riken.jp/0008852I129P2OlaHsdC57BL6Apoetm3APOE4MaeApoetm3APOE4MaeApoetm3APOE4Mae
• abnormal Bruch membrane morphology_Apoe<tm1(APOE*2)Mae>/Apoe<tm1(APOE*2)Mae>
  http://metadb.riken.jp/0005239I129P2OlaHsdC57BL6Apoetm1APOE2MaeApoetm1APOE2MaeApoetm1APOE2Mae
• amyloid beta deposits_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>
  http://metadb.riken.jp/0003329I129P2OlaHsdC57BL6Apoetm3APOE4MaeApoetm3APOE4MaeApoetm3APOE4Mae