Anja. Köster, et.al., Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism., Endocrinology, 2005, 146

http://rdf.ncbi.nlm.nih.gov/pubmed/16081640

Anja. Köster, et.al., Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism., Endocrinology, 2005, 146

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(APOE-ANGPTL4)1Akos
  http://metadb.riken.jp/db/mgi_rdf/MGI:3611784
• Angptl4<tm1Akos>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3610613
• Angptl3<tm1Akos>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3610614

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating cholesterol level_Angptl4<tm1Akos>/Angptl4<tm1Akos>
  http://metadb.riken.jp/0005179I129P2OlaHsdC57BL6Angptl4tm1AkosAngptl4tm1AkosAngptl4tm1Akos
• increased lipoprotein lipase activity_Angptl3<tm1Akos>/Angptl3<tm1Akos>
  http://metadb.riken.jp/0011578I129S1Sv129X1SvJC57BL6Angptl3tm1AkosAngptl3tm1AkosAngptl3tm1Akos
• decreased circulating triglyceride level_Angptl3<tm1Akos>/Angptl3<tm1Akos>,Angptl4<tm1Akos>/Angptl4<tm1Akos>
  http://metadb.riken.jp/0002644I129P2OlaHsd129S1Sv129X1SvJC57BL6Angptl3tm1AkosAngptl3tm1AkosAngptl4tm1AkosAngptl4tm1AkosAngptl3tm1AkosAngptl4tm1Akos
• premature death_Angptl3<tm1Akos>/Angptl3<tm1Akos>,Angptl4<tm1Akos>/Angptl4<tm1Akos>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S1Sv129X1SvJC57BL6Angptl3tm1AkosAngptl3tm1AkosAngptl4tm1AkosAngptl4tm1AkosAngptl3tm1AkosAngptl4tm1Akos
• decreased circulating triglyceride level_Angptl3<tm1Akos>/Angptl3<tm1Akos>
  http://metadb.riken.jp/0002644I129S1Sv129X1SvJC57BL6Angptl3tm1AkosAngptl3tm1AkosAngptl3tm1Akos
• decreased circulating cholesterol level_Angptl3<tm1Akos>/Angptl3<tm1Akos>
  http://metadb.riken.jp/0005179I129S1Sv129X1SvJC57BL6Angptl3tm1AkosAngptl3tm1AkosAngptl3tm1Akos
• decreased lipoprotein lipase activity_Tg(APOE-ANGPTL4)1Akos/0
  http://metadb.riken.jp/0011579IC57BL6SJLTgAPOEANGPTL41Akos0TgAPOEANGPTL41Akos
• decreased body size_Angptl3<tm1Akos>/Angptl3<tm1Akos>,Angptl4<tm1Akos>/Angptl4<tm1Akos>
  http://metadb.riken.jp/0001265I129P2OlaHsd129S1Sv129X1SvJC57BL6Angptl3tm1AkosAngptl3tm1AkosAngptl4tm1AkosAngptl4tm1AkosAngptl3tm1AkosAngptl4tm1Akos
• increased lipoprotein lipase activity_Angptl4<tm1Akos>/Angptl4<tm1Akos>
  http://metadb.riken.jp/0011578I129P2OlaHsdC57BL6Angptl4tm1AkosAngptl4tm1AkosAngptl4tm1Akos
• increased circulating VLDL cholesterol level_Tg(APOE-ANGPTL4)1Akos/0
  http://metadb.riken.jp/0005145IC57BL6SJLTgAPOEANGPTL41Akos0TgAPOEANGPTL41Akos
• decreased circulating cholesterol level_Angptl3<tm1Akos>/Angptl3<tm1Akos>,Angptl4<tm1Akos>/Angptl4<tm1Akos>
  http://metadb.riken.jp/0005179I129P2OlaHsd129S1Sv129X1SvJC57BL6Angptl3tm1AkosAngptl3tm1AkosAngptl4tm1AkosAngptl4tm1AkosAngptl3tm1AkosAngptl4tm1Akos
• increased circulating cholesterol level_Tg(APOE-ANGPTL4)1Akos/0
  http://metadb.riken.jp/0005178IC57BL6SJLTgAPOEANGPTL41Akos0TgAPOEANGPTL41Akos
• perinatal lethality, incomplete penetrance_Angptl3<tm1Akos>/Angptl3<tm1Akos>,Angptl4<tm1Akos>/Angptl4<tm1Akos>
  http://metadb.riken.jp/0011090I129P2OlaHsd129S1Sv129X1SvJC57BL6Angptl3tm1AkosAngptl3tm1AkosAngptl4tm1AkosAngptl4tm1AkosAngptl3tm1AkosAngptl4tm1Akos
• increased circulating triglyceride level_Tg(APOE-ANGPTL4)1Akos/0
  http://metadb.riken.jp/0001552IC57BL6SJLTgAPOEANGPTL41Akos0TgAPOEANGPTL41Akos
• decreased circulating triglyceride level_Angptl4<tm1Akos>/Angptl4<tm1Akos>
  http://metadb.riken.jp/0002644I129P2OlaHsdC57BL6Angptl4tm1AkosAngptl4tm1AkosAngptl4tm1Akos

class

http://purl.org/net/cito/citesAsAuthority

• Tg(APOE-ANGPTL4)1Akos
  http://metadb.riken.jp/db/mgi_rdf/MGI:3611784
• Angptl4<tm1Akos>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3610613
• Angptl3<tm1Akos>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3610614