Jane. Yoo, et.al., Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin., The Journal of experimental medicine, 2005, 202

http://rdf.ncbi.nlm.nih.gov/pubmed/16103410

Jane. Yoo, et.al., Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin., The Journal of experimental medicine, 2005, 202

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO/CMV-Tslp)#Sfz
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317863

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO/CMV-Tslp)#Sfz
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317863

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased IgG1 level_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0008499IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• thick epidermis_Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0001219I129P2OlaHsdC3HC57BL6FVBNTcrbtm1MomTcrbtm1MomTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgKRT5rtTA1GlkTcrbtm1MomTgtetOCMVTslpSfz
• conjunctivitis_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0001852IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• dry skin_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0003853IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• abnormal lymph node morphology_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0002339IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• decreased IgE level_Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0002492I129P2OlaHsdC3HC57BL6FVBNTcrbtm1MomTcrbtm1MomTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgKRT5rtTA1GlkTcrbtm1MomTgtetOCMVTslpSfz
• acanthosis_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0001874IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• skin inflammation_Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0004947I129P2OlaHsdC3HC57BL6FVBNTcrbtm1MomTcrbtm1MomTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgKRT5rtTA1GlkTcrbtm1MomTgtetOCMVTslpSfz
• enlarged spleen_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0000691IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• reddish skin_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0001190IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• abnormal cytokine level_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0008713IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• dermatitis_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0001194IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• epidermal spongiosis_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0009795IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• abnormal dermal layer morphology_Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0001243I129P2OlaHsdC3HC57BL6FVBNTcrbtm1MomTcrbtm1MomTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgKRT5rtTA1GlkTcrbtm1MomTgtetOCMVTslpSfz
• decreased IgG2a level_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0008496IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• hyperkeratosis_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0001242IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• increased CD4-positive, alpha beta T cell number_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0008074IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• increased IgE level_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0002497IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• skin lesions_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0001212IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk
• enlarged lymph nodes_Tg(KRT5-rtTA)1Glk/0,Tg(tetO/CMV-Tslp)#Sfz/0
  http://metadb.riken.jp/0000702IC3HC57BL6FVBNTgKRT5rtTA1Glk0TgtetOCMVTslpSfz0TgtetOCMVTslpSfzTgKRT5rtTA1Glk