Andrew M. Holland, et.al., Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas., Diabetes, 2005, 54

http://rdf.ncbi.nlm.nih.gov/pubmed/16123346

Andrew M. Holland, et.al., Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas., Diabetes, 2005, 54

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating glucose level_Pdx1<tm1Macd>/Pdx1<tm1Macd>,Tg(tetO-Ipf1,EGFP)956.6Macd/0
  http://metadb.riken.jp/0005560I129S1Sv129X1SvJC57BL6SJLPdx1tm1MacdPdx1tm1MacdTgtetOIpf1EGFP9566Macd0Pdx1tm1MacdTgtetOIpf1EGFP9566Macd
• impaired glucose tolerance_Pdx1<tm1Macd>/Pdx1<tm1Macd>,Tg(tetO-Ipf1,EGFP)956.6Macd/0
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJC57BL6SJLPdx1tm1MacdPdx1tm1MacdTgtetOIpf1EGFP9566Macd0Pdx1tm1MacdTgtetOIpf1EGFP9566Macd
• increased glucagon secretion_Pdx1<tm1Macd>/Pdx1<tm1Macd>,Tg(tetO-Ipf1,EGFP)956.6Macd/0
  http://metadb.riken.jp/0002710I129S1Sv129X1SvJC57BL6SJLPdx1tm1MacdPdx1tm1MacdTgtetOIpf1EGFP9566Macd0Pdx1tm1MacdTgtetOIpf1EGFP9566Macd
• increased cell proliferation_Pdx1<tm1Macd>/Pdx1<tm1Macd>,Tg(tetO-Ipf1,EGFP)956.6Macd/0
  http://metadb.riken.jp/0000351I129S1Sv129X1SvJC57BL6SJLPdx1tm1MacdPdx1tm1MacdTgtetOIpf1EGFP9566Macd0Pdx1tm1MacdTgtetOIpf1EGFP9566Macd
• small pancreatic islets_Pdx1<tm1Macd>/Pdx1<tm1Macd>,Tg(tetO-Ipf1,EGFP)956.6Macd/0
  http://metadb.riken.jp/0009172I129S1Sv129X1SvJC57BL6SJLPdx1tm1MacdPdx1tm1MacdTgtetOIpf1EGFP9566Macd0Pdx1tm1MacdTgtetOIpf1EGFP9566Macd
• abnormal pancreatic beta cell morphology_Pdx1<tm1Macd>/Pdx1<tm1Macd>,Tg(tetO-Ipf1,EGFP)956.6Macd/0
  http://metadb.riken.jp/0005217I129S1Sv129X1SvJC57BL6SJLPdx1tm1MacdPdx1tm1MacdTgtetOIpf1EGFP9566Macd0Pdx1tm1MacdTgtetOIpf1EGFP9566Macd
• impaired glucose tolerance_Pdx1<tm1Macd>/Pdx1<+>
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJPdx1tm1MacdPdx1Pdx1Pdx1tm1Macd
• decreased insulin secretion_Pdx1<tm1Macd>/Pdx1<tm1Macd>,Tg(tetO-Ipf1,EGFP)956.6Macd/0
  http://metadb.riken.jp/0003059I129S1Sv129X1SvJC57BL6SJLPdx1tm1MacdPdx1tm1MacdTgtetOIpf1EGFP9566Macd0Pdx1tm1MacdTgtetOIpf1EGFP9566Macd