Alexander. McCampbell, et.al., Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy., Human molecular genetics, 2005, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/16210380

Alexander. McCampbell, et.al., Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy., Human molecular genetics, 2005, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-Spltc1)6FAmcc
  http://metadb.riken.jp/db/mgi_rdf/MGI:4418352
• Tg(CAG-SPTLC1*C133W)8EAmcc
  http://metadb.riken.jp/db/mgi_rdf/MGI:4418339

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• reduced fertility_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0001921IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• abnormal neurite morphology_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0008415IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• exocrine pancreas atrophy_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0009164IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• abnormal behavior_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0004924IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• abnormal ventral spinal root morphology_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0003993IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• abnormal spermatogenesis_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0001156IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• abnormal intestinal transit time_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0006001IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• abnormal axon morphology_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0005404IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• abnormal pancreas morphology_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0001944IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• decreased body size_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0001265IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• abnormal myelin sheath morphology_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0003871IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• decreased thermal nociceptive threshold_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0003998IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc
• abnormal defecation_Tg(CAG-SPTLC1*C133W)8EAmcc/0
  http://metadb.riken.jp/0003866IC3HC57BL6TgCAGSPTLC1C133W8EAmcc0TgCAGSPTLC1C133W8EAmcc

class

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-Spltc1)6FAmcc
  http://metadb.riken.jp/db/mgi_rdf/MGI:4418352
• Tg(CAG-SPTLC1*C133W)8EAmcc
  http://metadb.riken.jp/db/mgi_rdf/MGI:4418339

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD19629
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD19629