Nicholas. Joza, et.al., Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy., Molecular and cellular biology, 2005, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/16287843

Nicholas. Joza, et.al., Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy., Molecular and cellular biology, 2005, 25

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Aifm1<tm2Pngr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686777

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardial fiber morphology_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0000278I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• increased skeletal muscle fiber diameter_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0009401I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• abnormal aerobic respiration_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0010957I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• decreased skeletal muscle mass_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0004819I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• increased mitochondria number_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0011628I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• muscle degeneration_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0000749I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• abnormal mitochondrial ATP synthesis coupled electron transport_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0010956I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• abnormal heart ventricle pressure_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0008775I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• cardiac hypertrophy_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0001625I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• decreased body size_Aifm1<tm2Pngr>/Aifm1<+>,Tmem163<Tg(ACTB-cre)2Mrt>/0
  http://metadb.riken.jp/0001265I129P2OlaHsdFVBNAifm1tm2PngrAifm1Tmem163TgACTBcre2Mrt0Tmem163TgACTBcre2MrtAifm1tm2PngrAifm1
• abnormal mitochondrial physiology_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0006036I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• dilated cardiomyopathy_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0002795I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• enlarged heart_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0000274I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• increased circulating lactate level_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0013405I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• oxidative stress_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0003674I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• prenatal lethality, incomplete penetrance_Aifm1<tm2Pngr>/Aifm1<+>,Tmem163<Tg(ACTB-cre)2Mrt>/0
  http://metadb.riken.jp/0011101I129P2OlaHsdFVBNAifm1tm2PngrAifm1Tmem163TgACTBcre2Mrt0Tmem163TgACTBcre2MrtAifm1tm2PngrAifm1
• abnormal glucose homeostasis_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0002078I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• lethargy_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0005202I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• enlarged myocardial fiber_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0004564I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• abnormal respiratory electron transport chain_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0010955I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• muscular atrophy_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0002269I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• abnormal hormone level_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0003953I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• abnormal mitochondrial crista morphology_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0011635I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• decreased catalase activity_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0011594I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• embryonic growth retardation_Aifm1<tm2Pngr>/Y,Tmem163<Tg(ACTB-cre)2Mrt>/0
  http://metadb.riken.jp/0003984I129P2OlaHsdFVBNAifm1tm2PngrYTmem163TgACTBcre2Mrt0Aifm1tm2PngrTmem163TgACTBcre2Mrt
• abnormal skeletal muscle fiber morphology_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0003084I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• embryonic lethality during organogenesis, complete penetrance_Aifm1<tm2Pngr>/Y,Tmem163<Tg(ACTB-cre)2Mrt>/0
  http://metadb.riken.jp/0011098I129P2OlaHsdFVBNAifm1tm2PngrYTmem163TgACTBcre2Mrt0Aifm1tm2PngrTmem163TgACTBcre2Mrt
• decreased cardiac muscle contractility_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0005140I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• abnormal mitochondrion morphology_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0006035I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn
• weight loss_Aifm1<tm2Pngr>/Y,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0001263I129P2OlaHsdFVBAifm1tm2PngrYTgCkmmcre5Khn0Aifm1tm2PngrTgCkmmcre5Khn

class

http://purl.org/net/cito/citesAsAuthority

• Aifm1<tm2Pngr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686777