Martin. Ramsden, et.al., Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L)., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/16291936

Martin. Ramsden, et.al., Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L)., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, 25

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased exploration in new environment_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0001417IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• astrocytosis_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0003354IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• hippocampal neuron degeneration_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0000811IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• neurofibrillary tangles_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0003214IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• hunched posture_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0001505IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• abnormal corticospinal tract morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0002878IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• weight loss_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0001263IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• impaired swimming_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0001522IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• abnormal spinal cord morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0000955IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• abnormal spatial reference memory_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0008414IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• neuron degeneration_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0003224IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• dystonia_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0005323IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• abnormal gait_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0001406IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• forebrain atrophy_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0012508IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• impaired coordination_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0001405IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• decreased brain weight_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0002175IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• tau protein deposits_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0004250IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha
• limb grasping_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*P301L)#Kha/0
  http://metadb.riken.jp/0001513IFVBNTgCamk2atTA1Mmay0TgtetOMAPTP301LKha0TgCamk2atTA1MmayTgtetOMAPTP301LKha