Frank. Rosenbauer, et.al., Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1., Nature genetics, 2006, 38

http://rdf.ncbi.nlm.nih.gov/pubmed/16311598

Frank. Rosenbauer, et.al., Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1., Nature genetics, 2006, 38

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Spi1<tm1.3Dgt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3619530

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased pre-B cell number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0008209I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• abnormal double-negative T cell morphology_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0002407I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• abnormal T cell subpopulation ratio_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0003944I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• decreased T cell number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0005018I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• decreased mature B cell number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0008211I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• increased T cell derived lymphoma incidence_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0002024I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• increased T cell number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0005015I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• increased IgM level_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0002494I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• increased leukemia incidence_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0002026I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• decreased thymocyte number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0000715I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• decreased B-1a cell number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0008168I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• decreased pro-B cell number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0008208I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• premature death_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• decreased granulocyte number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0000334I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• increased lymphocyte cell number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0005013I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• small thymus_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0000706I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• increased B-1 B cell number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0004977I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• arrested B cell differentiation_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0001802I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt
• increased B-1b cell number_Spi1<tm1.3Dgt>/Spi1<tm1.3Dgt>
  http://metadb.riken.jp/0008169I129S1Sv129X1SvJBALBcC57BL6Spi1tm13DgtSpi1tm13DgtSpi1tm13Dgt

class

http://purl.org/net/cito/citesAsAuthority

• Spi1<tm1.3Dgt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3619530