Douglas G. Howe, et.al., Inhibition of protein kinase A in murine enteric neurons causes lethal intestinal pseudo-obstruction., Journal of neurobiology, 2006, 66

http://rdf.ncbi.nlm.nih.gov/pubmed/16329126

Douglas G. Howe, et.al., Inhibition of protein kinase A in murine enteric neurons causes lethal intestinal pseudo-obstruction., Journal of neurobiology, 2006, 66

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prkar1a<tm2Gsm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3845256

class

http://purl.org/net/cito/citesAsAuthority

• Prkar1a<tm2Gsm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3845256

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• intestinal hypoperistalsis_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tlx2<tm1.1(cre)Rpk>/Tlx2<+>
  http://metadb.riken.jp/0003290I129S4SvJae129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTlx2tm11creRpkTlx2Tlx2tm11creRpkTlx2Prkar1atm2Gsm
• decreased white adipose tissue amount_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0001783I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• muscular atrophy_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0002269I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• blepharoptosis_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0001344I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• premature death_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0002083I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• abnormal small intestinal transit time_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0006002I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• abnormal small intestinal transit time_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tlx2<tm1.1(cre)Rpk>/Tlx2<+>
  http://metadb.riken.jp/0006002I129S4SvJae129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTlx2tm11creRpkTlx2Tlx2tm11creRpkTlx2Prkar1atm2Gsm
• abnormal small intestine morphology_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0000496I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• dry eyes_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0001337I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• intestinal obstruction_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tlx2<tm1.1(cre)Rpk>/Tlx2<+>
  http://metadb.riken.jp/0003270I129S4SvJae129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTlx2tm11creRpkTlx2Tlx2tm11creRpkTlx2Prkar1atm2Gsm
• distended duodenum_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tlx2<tm1.1(cre)Rpk>/Tlx2<+>
  http://metadb.riken.jp/0011881I129S4SvJae129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTlx2tm11creRpkTlx2Tlx2tm11creRpkTlx2Prkar1atm2Gsm
• distended abdomen_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0001270I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• decreased body weight_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0001262I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• short snout_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0000445I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal
• abnormal nose morphology_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Plp1-cre)1Bzal/0
  http://metadb.riken.jp/0002233I129X1SvJC57BL6C57BL6NDBA2Prkar1atm2GsmPrkar1atm2GsmTgPlp1cre1Bzal0Prkar1atm2GsmTgPlp1cre1Bzal