Chongjuan. Wei, et.al., Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis., Cancer research, 2005, 65

http://rdf.ncbi.nlm.nih.gov/pubmed/16357136

Chongjuan. Wei, et.al., Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis., Cancer research, 2005, 65

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Stk11<tm1.1Mlfr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612540
• Stk11<tm1.3Mlfr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612542
• Stk11<tm1.2Mlfr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612541

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• gastric polyps_Stk11<tm1.1Mlfr>/Stk11<+>
  http://metadb.riken.jp/0003299I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Stk11Stk11tm11Mlfr
• premature death_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002083I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53Stk11tm11MlfrStk11Trp53tm1TyjTrp53
• increased osteosarcoma incidence_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0003789I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53Stk11tm11MlfrStk11Trp53tm1TyjTrp53
• gastric polyps_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0003299I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53Stk11tm11MlfrStk11Trp53tm1TyjTrp53
• increased sarcoma incidence_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002032I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53Stk11tm11MlfrStk11Trp53tm1TyjTrp53
• visceromegaly_Stk11<tm1.1Mlfr>/Stk11<+>
  http://metadb.riken.jp/0013328I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Stk11Stk11tm11Mlfr
• colon polyps_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003269I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53tm1TyjTrp53tm1TyjStk11Stk11tm11Mlfr
• increased lymphoma incidence_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0012431I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53Stk11tm11MlfrStk11Trp53tm1TyjTrp53
• embryonic lethality, complete penetrance_Stk11<tm1.1Mlfr>/Stk11<tm1.1Mlfr>
  http://metadb.riken.jp/0011092I129S7SvEvBrdC57BL6JStk11tm11MlfrStk11tm11MlfrStk11tm11Mlfr
• abnormal intestine morphology_Stk11<tm1.1Mlfr>/Stk11<+>
  http://metadb.riken.jp/0000477I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Stk11Stk11tm11Mlfr
• distended abdomen_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0001270I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53Stk11tm11MlfrStk11Trp53tm1TyjTrp53
• enlarged liver_Stk11<tm1.1Mlfr>/Stk11<+>
  http://metadb.riken.jp/0000599I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Stk11Stk11tm11Mlfr
• enlarged spleen_Stk11<tm1.1Mlfr>/Stk11<+>
  http://metadb.riken.jp/0000691I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Stk11Stk11tm11Mlfr
• increased hamartoma incidence_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0010306I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53Stk11tm11MlfrStk11Trp53tm1TyjTrp53
• decreased tumor incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002052I129S2SvPas129S7SvEvBrdC57BL6JTrp53tm1TyjTrp53tm1TyjTrp53tm1Tyj
• increased hamartoma incidence_Stk11<tm1.1Mlfr>/Stk11<+>
  http://metadb.riken.jp/0010306I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Stk11Stk11tm11Mlfr
• enlarged stomach_Stk11<tm1.1Mlfr>/Stk11<+>
  http://metadb.riken.jp/0003883I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Stk11Stk11tm11Mlfr
• distended abdomen_Stk11<tm1.1Mlfr>/Stk11<+>
  http://metadb.riken.jp/0001270I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Stk11Stk11tm11Mlfr
• increased hamartoma incidence_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0010306I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53tm1TyjTrp53tm1TyjStk11Stk11tm11Mlfr
• premature death_Stk11<tm1.1Mlfr>/Stk11<+>
  http://metadb.riken.jp/0002083I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Stk11Stk11tm11Mlfr
• premature death_Stk11<tm1.1Mlfr>/Stk11<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002083I129S2SvPas129S7SvEvBrdC57BL6JStk11tm11MlfrStk11Trp53tm1TyjTrp53tm1TyjTrp53tm1TyjStk11Stk11tm11Mlfr

class

http://purl.org/net/cito/citesAsAuthority

• Stk11<tm1.1Mlfr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612540
• Stk11<tm1.3Mlfr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612542
• Stk11<tm1.2Mlfr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612541