Anton J M. Roebroek, et.al., Mutant Lrp1 knock-in mice generated by recombinase-mediated cassette exchange reveal differential importance of the NPXY motifs in the intracellular domain of LRP1 for normal fetal development., Molecular and cellular biology, 2006, 26

http://rdf.ncbi.nlm.nih.gov/pubmed/16382151

Anton J M. Roebroek, et.al., Mutant Lrp1 knock-in mice generated by recombinase-mediated cassette exchange reveal differential importance of the NPXY motifs in the intracellular domain of LRP1 for normal fetal development., Molecular and cellular biology, 2006, 26

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lrp1<tm2Ajmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830330
• Lrp1<tm3Ajmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830332
• Lrp1<tm4Ajmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830333
• Lrp1<tm1Ajmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830336

class

http://purl.org/net/cito/citesAsAuthority

• Lrp1<tm2Ajmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830330
• Lrp1<tm3Ajmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830332
• Lrp1<tm4Ajmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830333
• Lrp1<tm1Ajmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830336

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lethality throughout fetal growth and development, incomplete penetrance_Lrp1<tm3Ajmr>/Lrp1<tm3Ajmr>
  http://metadb.riken.jp/0011109I129P2OlaHsdC57BL6Lrp1tm3AjmrLrp1tm3AjmrLrp1tm3Ajmr
• decreased hepatocyte number_Lrp1<tm3Ajmr>/Lrp1<tm3Ajmr>
  http://metadb.riken.jp/0000606I129P2OlaHsdC57BL6Lrp1tm3AjmrLrp1tm3AjmrLrp1tm3Ajmr
• perinatal lethality, complete penetrance_Lrp1<tm3Ajmr>/Lrp1<tm3Ajmr>
  http://metadb.riken.jp/0011089I129P2OlaHsdC57BL6Lrp1tm3AjmrLrp1tm3AjmrLrp1tm3Ajmr
• liver degeneration_Lrp1<tm3Ajmr>/Lrp1<tm3Ajmr>
  http://metadb.riken.jp/0003103I129P2OlaHsdC57BL6Lrp1tm3AjmrLrp1tm3AjmrLrp1tm3Ajmr
• no abnormal phenotype detected_Lrp1<tm4Ajmr>/Lrp1<tm4Ajmr>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6Lrp1tm4AjmrLrp1tm4AjmrLrp1tm4Ajmr
• abnormal liver perisinusoidal space morphology_Lrp1<tm3Ajmr>/Lrp1<tm3Ajmr>
  http://metadb.riken.jp/0008988I129P2OlaHsdC57BL6Lrp1tm3AjmrLrp1tm3AjmrLrp1tm3Ajmr
• abnormal liver morphology_Lrp1<tm2Ajmr>/Lrp1<tm2Ajmr>
  http://metadb.riken.jp/0000598I129P2OlaHsdC57BL6Lrp1tm2AjmrLrp1tm2AjmrLrp1tm2Ajmr
• no abnormal phenotype detected_Lrp1<tm1Ajmr>/Lrp1<tm1Ajmr>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6Lrp1tm1AjmrLrp1tm1AjmrLrp1tm1Ajmr