Lawryn H. Kasper, et.al., Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development., Molecular and cellular biology, 2006, 26

http://rdf.ncbi.nlm.nih.gov/pubmed/16428436

Lawryn H. Kasper, et.al., Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development., Molecular and cellular biology, 2006, 26

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ep300<tm2Pkb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3526150

class

http://purl.org/net/cito/citesAsAuthority

• Ep300<tm2Pkb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3526150

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005018I129C57BL6CBACrebbptm1JvdCrebbptm1JvdTgLckcre548Jxm0Crebbptm1JvdTgLckcre548Jxm
• abnormal T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Ep300<tm2Pkb>/Ep300<tm2Pkb>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0006387I129P2OlaHsdC57BL6CBACrebbptm1JvdCrebbptm1JvdEp300tm2PkbEp300tm2PkbTgLckcre548Jxm0Crebbptm1JvdTgLckcre548JxmEp300tm2Pkb
• increased T cell derived lymphoma incidence_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0002024I129C57BL6CBACrebbptm1JvdCrebbptm1JvdTgLckcre548Jxm0Crebbptm1JvdTgLckcre548Jxm
• increased double-negative T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Ep300<tm2Pkb>/Ep300<tm2Pkb>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005090I129P2OlaHsdC57BL6CBACrebbptm1JvdCrebbptm1JvdEp300tm2PkbEp300tm2PkbTgLckcre548Jxm0Crebbptm1JvdTgLckcre548JxmEp300tm2Pkb
• decreased CD4-positive, alpha beta T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008075I129C57BL6CBACrebbptm1JvdCrebbptm1JvdTgLckcre548Jxm0Crebbptm1JvdTgLckcre548Jxm
• decreased thymocyte number_Ep300<tm2Pkb>/Ep300<tm2Pkb>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0000715I129P2OlaHsdC57BL6CBAEp300tm2PkbEp300tm2PkbTgLckcre548Jxm0Ep300tm2PkbTgLckcre548Jxm
• small thymus_Ep300<tm2Pkb>/Ep300<tm2Pkb>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0000706I129P2OlaHsdC57BL6CBAEp300tm2PkbEp300tm2PkbTgLckcre548Jxm0Ep300tm2PkbTgLckcre548Jxm
• small thymus_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0000706I129C57BL6CBACrebbptm1JvdCrebbptm1JvdTgLckcre548Jxm0Crebbptm1JvdTgLckcre548Jxm
• decreased single-positive T cell number_Ep300<tm2Pkb>/Ep300<tm2Pkb>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008083I129P2OlaHsdC57BL6CBAEp300tm2PkbEp300tm2PkbTgLckcre548Jxm0Ep300tm2PkbTgLckcre548Jxm
• decreased thymocyte number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0000715I129C57BL6CBACrebbptm1JvdCrebbptm1JvdTgLckcre548Jxm0Crebbptm1JvdTgLckcre548Jxm
• increased double-positive T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005091I129C57BL6CBACrebbptm1JvdCrebbptm1JvdTgLckcre548Jxm0Crebbptm1JvdTgLckcre548Jxm
• decreased double-positive T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Ep300<tm2Pkb>/Ep300<tm2Pkb>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6CBACrebbptm1JvdCrebbptm1JvdEp300tm2PkbEp300tm2PkbTgLckcre548Jxm0Crebbptm1JvdTgLckcre548JxmEp300tm2Pkb
• increased double-positive T cell number_Ep300<tm2Pkb>/Ep300<tm2Pkb>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005091I129P2OlaHsdC57BL6CBAEp300tm2PkbEp300tm2PkbTgLckcre548Jxm0Ep300tm2PkbTgLckcre548Jxm