Gergana. Galabova-Kovacs, et.al., Essential role of B-Raf in ERK activation during extraembryonic development., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

http://rdf.ncbi.nlm.nih.gov/pubmed/16432225

Gergana. Galabova-Kovacs, et.al., Essential role of B-Raf in ERK activation during extraembryonic development., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Raf1<tm2.1Bacc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3622475
• Braf<tm1.1Sva>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3622462

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal placenta labyrinth morphology_Braf<tm1.1Sva>/Braf<tm1.1Sva>
  http://metadb.riken.jp/0001716I129S1Sv129T2SvEms129X1SvJBraftm11SvaBraftm11SvaBraftm11Sva
• abnormal placenta morphology_Braf<tm1.1Sva>/Braf<tm1.1Sva>
  http://metadb.riken.jp/0001711I129S1Sv129T2SvEms129X1SvJBraftm11SvaBraftm11SvaBraftm11Sva
• prenatal lethality, complete penetrance_Meox2<tm1(cre)Sor>/Meox2<+>,Raf1<tm2Bacc>/Raf1<tm2.1Bacc>
  http://metadb.riken.jp/0011091I129P2OlaHsd129S4SvJaeSorMeox2tm1creSorMeox2Raf1tm2BaccRaf1tm21BaccRaf1tm21BaccMeox2Raf1tm2BaccMeox2tm1creSor
• abnormal spongiotrophoblast layer morphology_Braf<tm1.1Sva>/Braf<tm1.1Sva>
  http://metadb.riken.jp/0004255I129S1Sv129T2SvEms129X1SvJBraftm11SvaBraftm11SvaBraftm11Sva
• no abnormal phenotype detected_Braf<tm1Sva>/Braf<tm1Sva>,Tg(Tek-cre/ERT2)1Arnd/0
  http://metadb.riken.jp/0002169I129S1Sv129T2SvEms129X1SvJBraftm1SvaBraftm1SvaTgTekcreERT21Arnd0Braftm1SvaTgTekcreERT21Arnd
• abnormal trophoblast layer morphology_Braf<tm1.1Sva>/Braf<tm1.1Sva>
  http://metadb.riken.jp/0005031I129S1Sv129T2SvEms129X1SvJBraftm11SvaBraftm11SvaBraftm11Sva
• postnatal growth retardation_Braf<tm1Sva>/Braf<tm1.1Sva>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0001732I129S1Sv129S4SvJaeSor129X1SvJBraftm1SvaBraftm11SvaMeox2tm1creSorMeox2Meox2Meox2tm1creSorBraftm1SvaBraftm11Sva
• abnormal placental labyrinth vasculature morphology_Braf<tm1.1Sva>/Braf<tm1.1Sva>
  http://metadb.riken.jp/0008803I129S1Sv129T2SvEms129X1SvJBraftm11SvaBraftm11SvaBraftm11Sva
• decreased embryo size_Braf<tm1.1Sva>/Braf<tm1.1Sva>
  http://metadb.riken.jp/0001698I129S1Sv129T2SvEms129X1SvJBraftm11SvaBraftm11SvaBraftm11Sva
• lethality at weaning, complete penetrance_Braf<tm1Sva>/Braf<tm1.1Sva>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0011083I129S1Sv129S4SvJaeSor129X1SvJBraftm1SvaBraftm11SvaMeox2tm1creSorMeox2Meox2Meox2tm1creSorBraftm1SvaBraftm11Sva
• embryonic lethality during organogenesis, complete penetrance_Braf<tm1.1Sva>/Braf<tm1.1Sva>
  http://metadb.riken.jp/0011098I129S1Sv129T2SvEms129X1SvJBraftm11SvaBraftm11SvaBraftm11Sva

class

http://purl.org/net/cito/citesAsAuthority

• Raf1<tm2.1Bacc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3622475
• Braf<tm1.1Sva>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3622462