Raul. Mostoslavsky, et.al., Genomic instability and aging-like phenotype in the absence of mammalian SIRT6., Cell, 2006, 124

http://rdf.ncbi.nlm.nih.gov/pubmed/16439206

Raul. Mostoslavsky, et.al., Genomic instability and aging-like phenotype in the absence of mammalian SIRT6., Cell, 2006, 124

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sirt6<tm1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686893

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• spleen hypoplasia_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0000694I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• decreased cell proliferation_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0000352I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• lordosis_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0000162I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• decreased bone marrow cell number_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0000333I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• abnormal B cell differentiation_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0002144I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• colitis_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0002816I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• decreased circulating insulin-like growth factor I level_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0004701I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• increased cellular sensitivity to ionizing radiation_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0004227I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• spontaneous chromosome breakage_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0004029I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• decreased bone mineral density_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0000063I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• decreased body size_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0001265I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• abnormal lymphopoiesis_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0002401I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• decreased subcutaneous adipose tissue amount_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0008844I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• decreased leukocyte cell number_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0000221I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• increased cellular sensitivity to alkylating agents_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0008402I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• postnatal growth retardation_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0001732I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• decreased double-positive T cell number_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0005092I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• kyphosis_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0000160I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• lethality at weaning, complete penetrance_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0011083I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa
• decreased circulating glucose level_Sirt6<tm1Fwa>/Sirt6<tm1Fwa>
  http://metadb.riken.jp/0005560I129S6SvEvTac129X1SvJSirt6tm1FwaSirt6tm1FwaSirt6tm1Fwa

class

http://purl.org/net/cito/citesAsAuthority

• Sirt6<tm1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686893

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD24116
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD24116