Takuya. Nojima, et.al., Double knockout mice show BASH and PKCdelta have different epistatic relationships in B cell maturation and CD40-mediated activation., Immunology letters, 2006, 105

http://rdf.ncbi.nlm.nih.gov/pubmed/16481047

Takuya. Nojima, et.al., Double knockout mice show BASH and PKCdelta have different epistatic relationships in B cell maturation and CD40-mediated activation., Immunology letters, 2006, 105

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal plasma cell differentiation_Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008099I129P2OlaHsdC57BL6Prkcdtm1KinPrkcdtm1KinPrkcdtm1Kin
• decreased B-2 B cell number_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008207I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• decreased transitional stage B cell number_Blnk<tm1Dkit>/Blnk<tm1Dkit>
  http://metadb.riken.jp/0008190IC57BL6Blnktm1DkitBlnktm1DkitBlnktm1Dkit
• increased B cell proliferation_Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0005154I129P2OlaHsdC57BL6Prkcdtm1KinPrkcdtm1KinPrkcdtm1Kin
• increased IgG3 level_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008502I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• abnormal immunoglobulin level_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0002490I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• increased IgM level_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0002494I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• abnormal plasma cell differentiation_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008099I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• increased IgG1 level_Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008499I129P2OlaHsdC57BL6Prkcdtm1KinPrkcdtm1KinPrkcdtm1Kin
• decreased marginal zone B cell number_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008182I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• increased IgA level_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0002495I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• arrested B cell differentiation_Blnk<tm1Dkit>/Blnk<tm1Dkit>
  http://metadb.riken.jp/0001802IC57BL6Blnktm1DkitBlnktm1DkitBlnktm1Dkit
• arrested B cell differentiation_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0001802I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• decreased marginal zone B cell number_Blnk<tm1Dkit>/Blnk<tm1Dkit>
  http://metadb.riken.jp/0008182IC57BL6Blnktm1DkitBlnktm1DkitBlnktm1Dkit
• abnormal B cell apoptosis_Blnk<tm1Dkit>/Blnk<tm1Dkit>
  http://metadb.riken.jp/0008781IC57BL6Blnktm1DkitBlnktm1DkitBlnktm1Dkit
• increased B cell apoptosis_Blnk<tm1Dkit>/Blnk<tm1Dkit>
  http://metadb.riken.jp/0008782IC57BL6Blnktm1DkitBlnktm1DkitBlnktm1Dkit
• abnormal B cell proliferation_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0005153I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• decreased B-1 B cell number_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0004978I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• increased IgG2b level_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008501I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• increased marginal zone B cell number_Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008181I129P2OlaHsdC57BL6Prkcdtm1KinPrkcdtm1KinPrkcdtm1Kin
• decreased IgM level_Blnk<tm1Dkit>/Blnk<tm1Dkit>
  http://metadb.riken.jp/0001806IC57BL6Blnktm1DkitBlnktm1DkitBlnktm1Dkit
• abnormal immunoglobulin level_Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0002490I129P2OlaHsdC57BL6Prkcdtm1KinPrkcdtm1KinPrkcdtm1Kin
• decreased IgG3 level_Blnk<tm1Dkit>/Blnk<tm1Dkit>
  http://metadb.riken.jp/0008498IC57BL6Blnktm1DkitBlnktm1DkitBlnktm1Dkit
• decreased follicular B cell number_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008174I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• increased IgA level_Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0002495I129P2OlaHsdC57BL6Prkcdtm1KinPrkcdtm1KinPrkcdtm1Kin
• abnormal plasma cell differentiation_Blnk<tm1Dkit>/Blnk<tm1Dkit>
  http://metadb.riken.jp/0008099IC57BL6Blnktm1DkitBlnktm1DkitBlnktm1Dkit
• increased IgM level_Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0002494I129P2OlaHsdC57BL6Prkcdtm1KinPrkcdtm1KinPrkcdtm1Kin
• increased B cell apoptosis_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008782I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• increased IgG1 level_Blnk<tm1Dkit>/Blnk<tm1Dkit>,Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008499I129P2OlaHsdC57BL6NZBBlnktm1DkitBlnktm1DkitPrkcdtm1KinPrkcdtm1KinPrkcdtm1KinBlnktm1Dkit
• decreased follicular B cell number_Blnk<tm1Dkit>/Blnk<tm1Dkit>
  http://metadb.riken.jp/0008174IC57BL6Blnktm1DkitBlnktm1DkitBlnktm1Dkit
• increased transitional stage B cell number_Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008189I129P2OlaHsdC57BL6Prkcdtm1KinPrkcdtm1KinPrkcdtm1Kin
• increased follicular B cell number_Prkcd<tm1Kin>/Prkcd<tm1Kin>
  http://metadb.riken.jp/0008173I129P2OlaHsdC57BL6Prkcdtm1KinPrkcdtm1KinPrkcdtm1Kin

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased IgG1 level in RBRC00457
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000824
• abnormal immunoglobulin level in RBRC00457
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000805
• increased IgA level in RBRC00457
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000807
• increased B cell proliferation in RBRC00457
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000814
• increased IgM level in RBRC00457
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000806
• abnormal plasma cell differentiation in RBRC00457
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000817
• increased follicular B cell number in RBRC00457
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000818
• increased marginal zone B cell number in RBRC00457
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000819
• increased transitional stage B cell number in RBRC00457
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000820