Hongjie. Zhang, et.al., The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass., Molecular endocrinology (Baltimore, Md.), 2006, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/16556734

Hongjie. Zhang, et.al., The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass., Molecular endocrinology (Baltimore, Md.), 2006, 20

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal pancreatic beta cell morphology_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005217I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• decreased pancreas weight_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009109I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• pancreas necrosis_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009148I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• decreased pancreatic beta cell proliferation_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0011820I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• abnormal exocrine pancreas morphology_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005220I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• decreased pancreatic beta cell number_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003339I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• small pancreatic islets_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009172I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• impaired glucose tolerance_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005293I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• abnormal insulin secretion_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003564I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• abnormal glucose homeostasis_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0002078I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• abnormal pancreatic islet morphology_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005215I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• pancreas cysts_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003336I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• increased pancreatic alpha cell number_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009176I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam
• decreased pancreatic beta cell mass_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009114I129X1SvJC57BL6CBAFoxm1tm1RhcFoxm1tm1RhcTgPdx1cre891Dam0Foxm1tm1RhcTgPdx1cre891Dam