Omer H. Yilmaz, et.al., Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells., Nature, 2006, 441

http://rdf.ncbi.nlm.nih.gov/pubmed/16598206

Omer H. Yilmaz, et.al., Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells., Nature, 2006, 441

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone marrow cell number_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000333BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn
• increased acute lymphoblastic leukemia incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010336BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn
• enlarged thymus_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000709BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn
• increased leukemia incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002026BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn
• abnormal blood cell morphology/development_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002429BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn
• abnormal hematopoietic stem cell physiology_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010763BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn
• spleen hyperplasia_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000693BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn
• premature death_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn
• increased acute promyelocytic leukemia incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004049BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn
• extramedullary hematopoiesis_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000240BKSCgPtprcbThy1aTgMx1cre1CgnPtentm1HwuPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuTgMx1cre1Cgn